Strain Information | |
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Image | |
BRC No. | RBRC05673 |
Type | Spontaneous Mutation Congenic |
Species | Mus musculus |
Strain name | B6;Cg-Oca2<p-cas>/2Nga |
Former Common name | B6-p<cas>/B, B6.Cg-Oca2<p-cas>/B, p-cas-RED |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | Developed by Akira Ishikawa, Graduate School of Bioagricultural Science, Nagoya University in 2012. |
Strain description | B6JJcl congenic strain having a pink-eyed dilution derived from Mus mucsculus castaneous mice. The strain shows progressive darkening of the eyes and coat hair with aging. |
Colony maintenance | Homozygote x Homozygote Homozygous mice are viable and fertile. |
References | l-tyrosine induces melanocyte differentiation in novel pink-eyed dilution castaneus mouse mutant showing age-related pigmentation. Hirobe T, Ishikawa A J. Darmatol. Sci., 80, 203-211 (2015). 26475433A new spontaneous allele at the pink-eyed dilution (p) locus discovered in Mus musculus castaneus. Tsuji A, Wakayama T, Ishikawa A Exp. Anim., 44, 347-351 (1995). 8575552Development of a novel pink-eyed dilution mouse model showing progressive darkening of the eyes and coat hair with aging. Ishikawa A, Sugiyama M, Hondo E, Kinoshita K, Yamagishi Y Exp. Anim., 64 (2): 207-220 (2015). 25739360 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |||||||
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Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
Oca2 | oculocutaneous albinism II | 7 | Oca2 | pink-eyed dilution castaneus |
Phenotype | |
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Annotation by Mammalian phenotyhpe ontology | |
Detailed phenotype data |
Ordering Information | |
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Donor DNA | |
Research application | Dermatology Research Sensorineural Research |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Exp. Anim., 64(2): 207-220 (2015).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. For profit use of the BIOLOGICAL RESSOURCE, the RECIPIENT must contact with the Intellectual Property Office, Nagoya University to obtain a prior written consent. The RECIPIENT agrees to use this BIOLOGICAL RESOURCE as a collaboration with DEPOSITOR. The availability of the BIOLOGICAL RESOURCE is limited to a RECIPIENT of a not-for profit organization for a not-for-profit research. The RECIPIENT agrees to use the BIOLOGICAL RESOURCE only for scientific research for publishing paper(s). Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE. |
Depositor | Akira Ishikawa (Nagoya University) |
Strain Status | Frozen sperm |
Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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No Data |