Strain Data Sheet



BRC No.RBRC05556
TypeSpontaneous Mutation
SpeciesMus musculus
Strain nameB6J.MSM-Aanat<MSM>
Former Common nameB6-Aanat<MSM>
H-2 Haplotype
ES Cell line
Background strainC57BL/6JJcl
Strain developmentDeveloped by Takaoki Kasahara, RIKEN Brain Science Institute and Shigeharu Wakana, RIKEN BioResource Center in 2011. This congenic strain was generated by backcrossing to C57BL/6J from MSM/Ms.
Strain descriptionC57BL/6J congenic strain having Aanat gene derived from Japanese wild-derived inbred mice, MSM/Ms. Melatonin synthesis requires enzymes encoded by Aanat and Hiomt genes. B6J.MSM-Aanat<MSM> Hiomt<MSM> (RBRC05503), B6J.MSM-Aanat<MSM> (RBRC05556), B6J.MSM-Hiomt<MSM> (RBRC05557).
Colony maintenanceHomozygote x Homozygote
ReferencesProc. Natl. Acad. Sci. USA, 107, 6412-6417 (2010). 20308563
J. Pineal Res. (2021) DOI:10.1111/JPI.12748 34085306

Health Report

Examination Date / Room / Rack


Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Aanatarylalkylamine N-acetyltransferase11Aanat<MSM/Ms>MSM/Ms


Donor DNA
Research application
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. J Pineal Res. 2021 Jun 4;e12748.Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEVELOPER (Dr. Takaoki Kasahara) using the Approval Form.
DepositorTadafumi Kato (RIKEN)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Approval form (Japanese / English)
  2. Order form (Japanese / English)
  3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
Lab HP
Genotyping protocol -PCR-

BRC mice in Publications

No Data