Strain Information | |
---|---|
Image | |
BRC No. | RBRC05556 |
Type | Spontaneous Mutation |
Species | Mus musculus |
Strain name | B6J.MSM-Aanat<MSM> |
Former Common name | B6-Aanat<MSM> |
H-2 Haplotype | |
ES Cell line | |
Background strain | C57BL/6JJcl |
Appearance | |
Strain development | Developed by Takaoki Kasahara, RIKEN Brain Science Institute and Shigeharu Wakana, RIKEN BioResource Center in 2011. This congenic strain was generated by backcrossing to C57BL/6J from MSM/Ms. |
Strain description | C57BL/6J congenic strain having Aanat gene derived from Japanese wild-derived inbred mice, MSM/Ms. Melatonin synthesis requires enzymes encoded by Aanat and Hiomt genes. B6J.MSM-Aanat<MSM> Hiomt<MSM> (RBRC05503), B6J.MSM-Aanat<MSM> (RBRC05556), B6J.MSM-Hiomt<MSM> (RBRC05557). |
Colony maintenance | Homozygote x Homozygote |
References | Impact of endogenous melatonin on rhythmic behaviors, reproduction, and survival revealed in melatonin-proficient C57BL/6J congenic mice. Zhang C, Clough S J, Adamah-Biassi E B, Sveinsson M H, Hutchinson A J, Miura I, Furuse T, Wakana S, Matsumoto Y K, Okanoya K, Hudson R L, Kato T, Dubocovich M L, Kasahara T J. Pineal. Res., 71(2):e12748 (2021). 34085306Genetic variation of melatonin productivity in laboratory mice under domestication. Kasahara T, Abe K, Mekada K, Yoshiki A, Kato T Proc. Natl. Acad. Sci. USA, 107, 6412-6417 (2010). 20308563 |
Health Report | |
---|---|
Examination Date / Room / Rack |
Gene | |||||||
---|---|---|---|---|---|---|---|
Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
Aanat | arylalkylamine N-acetyltransferase | 11 | Aanat | MSM/Ms |
Phenotype | |
---|---|
Annotation by Mammalian phenotyhpe ontology | |
Detailed phenotype data |
Ordering Information | |
---|---|
Donor DNA | |
Research application | |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. J. Pineal. Res., 71(2):e12748 (2021). Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEVELOPER (Dr. Takaoki Kasahara) using the Approval Form. |
Depositor | Tadafumi Kato (RIKEN) |
Strain Status | Frozen sperm |
Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
---|
No Data |