Strain Data Sheet

RBRC05552

Strain Information

Image
BRC No.RBRC05552
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain name129S6.129S(Cg)-Grm6<tm1Nak>
Former Common name129-mGluR6 KO, 129-Grm6 KO
H-2 Haplotype
ES Cell lineCCE/EK.CCE [129S/SvEv-Gpi1<c>]
Background strain129S6/SvEvTac
Appearance
Strain development大阪バイオサイエンス研究所・中西 重忠先生, 古川 貴久先生 (2012)。B6-Grm6-lacZ Tg/Grm6 KOマウス (RBRC01353) より129S6/SvEvTacへ戻し交配された (12世代以上)。
Strain descriptionmGluR6 (Grm6) 遺伝子のノックアウトマウス。129背景。
Colony maintenanceHeterozygote x Homozygote [or Crossing to 129S6/SvEvTac]
ReferencesJ. Neurosci., 19, 2568-2579 (1999). 10087070
Cell, 80, 757-765 (1995). 7889569

Health Report

Examination Date / Room / Rack2022/05/31Room:4-CRack:L

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Grm6glutamate receptor, metabotropic 611Grm6<tm1Nak>targeted mutation 1, Shigetada Nakanishi

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
neoneomycin resistance gene (E. coli)11neo; neomycin;herpes simplex virus thymidine kinase promoter (HSV tk promoter)

Ordering Information

供与核酸E. coli Neomycin resistance gene, Herpes simplex virus thymidine kinase promoter (HSV tk promoter), Mouse Grm6 genomic DNA
Research applicationNeurobiology Research
提供条件条件を付加する。
研究成果の公表にあたって寄託者の指定する文献を引用する。Cell, 80, 757-765 (1995). J. Neurosci., 19, 2568-2579 (1999).
Depositor中西　重忠, 古川　貴久（(公財)大阪バイオサイエンス研究所）
Strain Status凍結胚のアイコン凍結胚
凍結精子のアイコン凍結精子
Strain Availability凍結胚より作出したマウスを2~4ヶ月以内に提供可能
凍結精子を1ヶ月以内に提供可能
凍結胚を1ヶ月以内に提供可能
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

Orlandi C, Omori Y, Wang Y, Cao Y, Ueno A, Roux MJ, Condomitti G, de Wit J, Kanagawa M, Furukawa T, Martemyanov KA.
Transsynaptic Binding of Orphan Receptor GPR179 to Dystroglycan-Pikachurin Complex Is Essential for the Synaptic Organization of Photoreceptors.
Cell Rep 25(1) 130-145.e5(2018) 30282023