Strain Data Sheet

RBRC05512

Strain Information

Image
BRC No.RBRC05512
TypeInbred
SpeciesMus musculus
Strain nameC57BL/10ScCr
Former Common nameB10ScCr
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDr. Cris Galanosより分与。 (1994年)
Strain descriptionTLR4欠損およびIL-12Rbeta2のpoint mutation
Colony maintenanceTlr4 : Homozygote x Homozygote ; Il12rb2 : Homozygote x Homozygote Homozygous mutant mice are viable and fertile.
ReferencesJ. Immunol., 167, 2106-2111 (2001). 11489994
Science, 282, 2085-2088 (1998). 9851930

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Tlr4toll-like receptor 44Tlr4<lps-del>toll-like receptor 4; defective lipopolysaccharide

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Il12rb2interleukin 12 receptor, beta 26Il12rb2<Ifnm-d>interferon response to microorgansisms, defective

Ordering Information

供与核酸
Research applicationImmunology and Inflammation Research
提供条件条件を付加しない。
Depositor滝本　博明（北里大学）
Strain Status凍結胚のアイコン凍結胚
Strain Availability凍結胚より作出したマウスを2~4ヶ月以内に提供可能
凍結胚を1ヶ月以内に提供可能
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

No Data