Strain Information | |
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Image | |
BRC No. | RBRC05498 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6.129P2-Samd9l<tm1Homy> |
Former Common name | TITAN KO |
H-2 Haplotype | |
ES Cell line | E14 [129P2/OlaHsd] |
Background strain | C57BL/6NCrlCrlj |
Appearance | |
Strain development | Developed by Hiroaki Honda, Research Institute for Radiation Biology and Medicine, Hiroshima University in 2006. E14 ES cells (129P2/OlaHsd) were used. The mutant mice were crossed to C57BL/6N mice. |
Strain description | Samd9L knockout mice. A part of Exon 2 of Samd9L gene was replaced with a lacZ-loxP-neo-loxP cassette. Homozygous mutant mice are viable and fertile. |
Colony maintenance | Heterozygote x Wild-type [C57BL/6NCrlCrlj] |
References | J. Invest. Dermatol., 131, 1428-1434 (2011). 21412262 Cancer Cell, 9;24(3):305-17 (2013). 24029230 Am. J. Hum. Genet., 79, 759-764 (2006). 16960814 Biochem. Biophys. Res. Commun., 383, 245-251 (2009). 19358830 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Samd9lsterile alpha motif domain containing 9-like6Samd9l <tm1Homy>targeted mutation 1, Hiroaki Honda Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter lacZbeta-galactosidase (E. coli)6 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP6loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP6loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)6neo; neomycin;herpes simplex virus thymidine kinase promoter (HSV tk promoter) |
Ordering Information | |
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Donor DNA | E. coli lacZ, poly A, Phage P1 loxP sites, herpes simplex virus thymidine kinase promoter (HSV tk promoter), E. coli neo, mouse Samd9l genomic DNA |
Research application | Cre/loxP system Fluorescent Proteins/lacZ System |
Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. |
Depositor | Hiroaki Honda (Tokyo Women's Medical University) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |