Strain Information | |
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Image | |
BRC No. | RBRC05456 |
Type | Spontaneous Mutation |
Species | Mus musculus |
Strain name | STOCK Dab1<yot> |
Former Common name | yotari |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | Arose in the descendants of a male chimeric mouse (chimera of 129 and C57BL/6JJcl) during the generation of P3R knockout mice. |
Strain description | Yotari mice, spontaneous and autosomal recessive mutant. Homozygous mutant mice show unstable gait and whole-body tremor due to hypoplastic cerebellum. This mutation was caused by a replacement of Dab1 gene sequence with a long interspersed nuclear element (L1) fragment. |
Colony maintenance | Heterozygote x Wild-type Homozygous mice exhibit ataxia. |
References | Neurosci. Res., 29, 217-223 (1997). 9436647 Mol. Brain Res., 75, 121-127 (2000). 10648895 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter |
Ordering Information | |
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Donor DNA | |
Research application | |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Brain. Res. Mol. Brain Res., 75, 121-127 (2000). および Neurosci. Res., 29, 217-223 (1997). |
Depositor | Kazunori Nakajima (Keio University) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |