Strain Information | |
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Image | |
BRC No. | RBRC05279 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | C57BL/6-Tg(Olfr16-Olr226*D126R/R127D,-Nrp1,-gapECFP)1Hsak/Rbrc |
Former Common name | I7(RDY)-ires-Nrp1-ires-gap-ECFP:IANC (Acc. No.CDB0449T) |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | Developed by Hitoshi Sakano, Graduate School of Science, University of Tokyo. |
Strain description | A mutant-type odorant receptor, I7 (D126R/R127D), Neuropilin-1, and an axonal marker gene, gap-ECFP, are expressed under MOR23 (Olfr16) gene promoter. |
Colony maintenance | Carrier x Noncarrier [C57BL/6N] |
References | Pre-target axon sorting establishes the neural map topography. Imai T, Yamazaki T, Kobayakawa R, Kobayakawa K, Abe T, Suzuki M, Sakano H Science,325, 585-590 (2009). 19589963 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |||||||
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Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
ECFP | Enhanced Cyan Fluorescent Protein (Aequorea victoria) | UN | ECFP | ||||
Gap43 | growth associated protein 43 | UN | Gap43 | ||||
Ires | internal ribosomal entry site (EMCV) | UN | |||||
Nrp1 | neuropilin 1 | UN | Nrp1 |
Phenotype | |
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Annotation by Mammalian phenotyhpe ontology | |
Detailed phenotype data |
Ordering Information | |
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Donor DNA | I7 (RDY) (rat), Encephalomyocarditis virus (EMCV) internal ribosomal entry site (ires), ECFP cDNA (Aequorea aequorea), Neuropilin-1, mouse gap43 palmitoylation signal |
Research application | Cell Biology Research Fluorescent Proteins/lacZ System covid19_infection |
Specific Term and Conditions | (1) The RECIPIENT shall obtain a prior agreement from the DEVELOPER (Dr. Hitoshi Sakano, The University of Tokyo, E-mail: sakano@mail.ecc.u-tokyo.ac.jp) to transfer the BIOLOGICAL RESOURCE. (2) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the Acc.No. CDB0449T and Web. Site (https://large.riken.jp/distribution/mutant-list.html) is requested. (3) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the literature designed by the DEPOSITOR is requested. (Science. 2009 325(5940):585-90.) (4) Please inform the DEPOSITOR (mutant.bdr@riken.jp) about the paper when published. |
Depositor | RIKEN CDB (RIKEN CDB) |
Strain Status | Frozen embryos |
Strain Availability | Recovery and QC required prior to distribution |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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No Data |