Strain Data Sheet

RBRC05106

Strain Information

Image
BRC No.RBRC05106
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6;129P2-Del(Oas1 Oas3 Oas2)1Yiw
Former Common name
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeveloped by Shigeru Kakuta and Yoichiro Iwakura, The Institute of Medical Science, The University of Tokyo in 2002. The mice were backcrossed to C57BL/6 for at least 8 times.
Strain descriptionOas1, Oas3 and Oas2 cluster knockout mice. Homozygous mutant mice show increased susceptibility to infection of subset of virus.
Colony maintenance
References

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Oas32'-5' oligoadenylate synthetase 35Oas3

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Oas22'-5' oligoadenylate synthetase 25Oas2

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Hyghygromycin phasphotransferase (E. coli)5Hyg

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Oas12'-5' oligoadenylate synthetase 15Oas1

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
loxPphage P1 loxP5loxP

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
loxPphage P1 loxP5loxP

Ordering Information

Donor DNAE. coli hygromycin resistance gene, Phosphoglycerate kinase (PGK) promoter (mouse), loxP (P1 Phage)
Research applicationImmunology and Inflammation Research
Specific Term and ConditionsPlease obtain the written consent from Professor Yoichiro Iwakura (iwakura@rs.tus.ac.jp; Research Institute for Biological Sciences, Tokyo University of Science) for the use.
DepositorYoichiro Iwakura (The University of Tokyo)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

BRC mice in Publications

No Data