Strain Data Sheet
RBRC05105
Strain Information | |
|---|---|
| Image | |
| BRC No. | RBRC05105 |
| Type | Targeted Mutation |
| Species | Mus musculus |
| Strain name | B6;129P2-Oas1a<tm1Yiw> Oas2<tm1Yiw> |
| Former Common name | |
| H-2 Haplotype | |
| ES Cell line | |
| Background strain | |
| Appearance | |
| Strain development | Developed by Shigeru Kakuta and Yoichiro Iwakura, The Institute of Medical Science, The University of Tokyo in 2002. The mice were backcrossed to C57BL/6 for at least 10 times. |
| Strain description | Oas1a and Oas2 double knockout mice. Homozygous mutant mice show increased susceptibility to infection of subset of virus. |
| Colony maintenance | |
| References | |
Health Report | |
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| Examination Date / Room / Rack | |
Gene | |
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| Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Hyghygromycin phasphotransferase (E. coli)5Hyg Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP5loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)5neo; neomycin; |
Ordering Information | |
|---|---|
| Donor DNA | Neomycin resistance gene, E. coli hygromycin resistance gene, Phosphoglycerate kinase (PGK) promoter (mouse), loxP (P1 Phage) |
| Research application | Immunology and Inflammation Research |
| Specific Term and Conditions | Please obtain the written consent from Professor Yoichiro Iwakura (iwakura@rs.tus.ac.jp; Research Institute for Biological Sciences, Tokyo University of Science) for the use. |
| Depositor | Yoichiro Iwakura (The University of Tokyo) |
| Strain Status |  Frozen sperm |
| Strain Availability |  Recovery and QC required prior to distribution |
| Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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