Strain Data Sheet

RBRC05102

Strain Information

Image
BRC No.RBRC05102
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6;129P2-Oas1a<tm1Yiw>
Former Common name
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeveloped by Shigeru Kakuta and Yoichiro Iwakura, The Institute of Medical Science, The University of Tokyo in 2002. The mice were backcrossed to C57BL/6 for at least 8 times.
Strain descriptionOas1a knockout mice. Homozygous mutant mice show increased susceptibility to infection of subset of virus.
Colony maintenance
References

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Oas1a2'-5' oligoadenylate synthetase 1A5Oas1a<tm1Yiw>targeted mutation 1, Yoichiro Iwakura

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
loxPphage P1 loxP5loxP

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
neoneomycin resistance gene (E. coli)5neo; neomycin;

Ordering Information

Donor DNANeomycin resistance gene (E. coli), Phosphoglycerate kinase (PGK) promoter (mouse), loxP (P1 Phage)
Research applicationImmunology and Inflammation Research
Specific Term and ConditionsPlease obtain the written consent from Professor Yoichiro Iwakura (iwakura@rs.tus.ac.jp; Research Institute for Biological Sciences, Tokyo University of Science) for the use.
DepositorYoichiro Iwakura (The University of Tokyo)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

BRC mice in Publications

No Data