Strain Data Sheet



BRC No.RBRC04940
SpeciesMus musculus
Strain nameB6.B6D2-Tg(Ins2-Tnf)
Former Common nameB6-Ins2-Tnf Tg (TNF-Tg)
H-2 Haplotype
ES Cell line
Background strain
Strain developmentDeveloped by Yasunori Higuchi, Centre Medical Unibersitaire, University oF Geneva in 1990.
Strain description
Colony maintenanceCarrier x Noncarrier [C57BL/6NJcl]
ReferencesJ. Exp. Med., 176, 1719-1731 (1992). 1460428
J. Immunol., 150, 5185-5194 (1993). 8496610

Health Report

Examination Date / Room / Racknull


Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Tnftumor necrosis factorUNTnftumor necrosis factor alpha, DIF, Tnfa, TNFSF2, TNFalpha, TNF-alpha, TNF alpha, Tnfsf1a, tumor necrosis factor-alpharat Insulin prommoter 2, SV40 polyA signal


Donor DNAMouse TNF-alpha genomic DNA, Rat Insulin prommoter 2, SV40 polyA signal
Research applicationDiabetes and Obesity Research
Specific Term and ConditionsNo specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
DepositorYasunori Higuchi (Oita University)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

No Data