Strain Information | |
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Image | |
BRC No. | RBRC04889 |
Type | Spontaneous Mutation |
Species | Mus musculus |
Strain name | MRL.CB-Fas<lpr-cg> |
Former Common name | MRL-lpr<cg> |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | Developed by Akio Matsuzawa, Institute of Medical Science in Tokyo. The mutant mice were baccrossed to MRL for 12 times. Deposited by Kazutoshi Sayama, Faculty of Agriculture, Shizuoka University. |
Strain description | CBA/KlJms系統で発見された自己免疫疾患Lpr<Cg>遺伝子のMRLコンジェニック系統。生後2ヶ月齢頃から、リンパ節の腫脹、皮膚炎症を伴う首から頭にかけての脱毛および皮膚の炎症を呈する。 |
Colony maintenance | Homozygote x Homozygote |
References | Immunology, 76, 498-504 (1992) . 1526655 Viral Immunol., 13, 297-311 (2000). 11016595 |
Health Report | |
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Examination Date / Room / Rack | 2024/01/22Room:3-CRack:A 2023/10/23Room:3-CRack:A 2023/07/24Room:3-CRack:A 2023/04/24Room:3-CRack:A 2023/01/23Room:3-CRack:A 2022/10/25Room:3-CRack:A 2022/08/22Room:3-CRack:A 2022/07/25Room:3-CRack:A |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter FasFas (TNF receptor superfamily member)19Fas<lpr-cg>lymphoproliferation complementing gldAPO-1, CD95, TNFR6, Tnfrsf6 |
Ordering Information | |
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供与核酸 | |
Research application | Immunology and Inflammation Research |
提供条件 | 条件を付加する。 研究成果の公表にあたって謝辞の表明を必要とする。 |
Depositor | 茶山 和敏(国立大学法人静岡大学) |
Strain Status | 生体 凍結胚 |
Strain Availability | 凍結胚を1ヶ月以内に提供可能 生体マウスを1~3ヶ月以内に提供可能 |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |