Strain Data Sheet

RBRC04820

Information1

Image
BRC No.RBRC04820
TypeTargeted Mutation and TransgeneCartagena
SpeciesMus musculus
Strain nameB6.Cg-Del(18Pcdha-Pcdhg) Tg(Taf7)/TyagRbrc
Former Common nameDelta Pcdhabg
H-2 Haplotype
ES Cell lineTT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1]
Background strain
Appearance
Strain developmentDeveloped by Takeshi Yagi, Graduate School of Frontier Biosciences, Osaka University in 2010.
Strain descriptionKO homozygous mutant mice are embryonic lethal. KO homozygous mutant mice with Tg allele are viable.
Colony maintenanceKO : Homozygote X Heterozygote ; Tg : Carrier X Carrier [or Crossing to C57BL/6J(Crlj)]
ReferencesFront. Mol. Neurosci., 9:155 (2016). 28066179

Health Report

Examination Date / Room / Rack2021/12/06Room:4-BRack:B
2021/09/08Room:4-BRack:B
2021/06/07Room:4-BRack:B
2021/03/22Room:4-BRack:B
2020/12/14Room:4-BRack:B
2020/10/05Room:4-BRack:B

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Pcdhaprotocadherin alpha cluster18Pcdha

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Pcdhgprotocadherin gamma cluster18Pcdhg

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
loxPphage P1 loxP18loxP

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Taf7TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factorUNTaf7transgene insertion

Information2

Donor DNAP1 phage loxP site, mouse Pcdh-abg genomic DNA, mouse Taf7 genomic DNA
Research applicationCre/loxP system
Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. If the RECIPIENT's research results in an invention based on the BIOLOGICAL RESOURCE, the RECIPIENT must contact DEPOSITOR to negotiate. In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, the RECIPIENT must obtain a prior written consent from the DEPOSITOR.
DepositorTakeshi Yagi (Osaka University)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved sperm (within 1 month)
Cryopreserved embryos (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Approval form (Japanese / English)
  2. Order form (Japanese / English)
  3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  4. Acceptance of responsibility for living modified organism (Japanese / English)
Lab HP (Japanese)
Genotyping protocol -PCR-

BRC mice in Publications

No Data