Strain Data Sheet

RBRC04802

Strain Information

Image
BRC No.RBRC04802
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.Cg-Bmper<tm1Ysas>/Rbrc
Former Common nameCv2(tau-lacZ) (Acc.No.CDB0402K)
H-2 Haplotype
ES Cell lineTT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1]
Background strain
Appearance
Strain developmentDeveloped by Dr. Yoshiki Sasai, Center for Developmental Biology, RIKEN.
Strain descriptionThis transgene contains tau-lacZ with a floxed neo in the first exon of Cv2 to replace with lacZ at the first ATG. Cv2 (Bmper : BMP-binding endothelial regulator) is essential for multiple organogenetic processes that involve Bmp signals. Cv2 homozygous mutant mice show effects in the vertebral column and eyes.
Colony maintenanceHeterozygote x Wild-type [C57BL/6] Homozygous mutant mice are neonatal lethal.
ReferencesDevelopment, 133, 4463-4473 (2006). 17035289

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
BmperBMP-binding endothelial regulator9Bmper<tm1Ysas>targeted mutation 1, Yoshiki Sasai

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
lacZbeta-galactosidase (E. coli)9

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
loxPphage P1 loxP9loxP

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
neoneomycin resistance gene (E. coli)9neo; neomycin;

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
poly ApolyA9poly A

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
taubovine tau protein cDNA9tau

Ordering Information

供与核酸LacZ (大腸菌), polyA (SV40), PGK promoter (mouse) Neo (大腸菌), loxP (P1ファージ), tau遺伝子 (ウシ)
Research applicationCre/loxP system
Fluorescent Proteins/lacZ System
提供条件条件を付加する。
(1) 分与希望者は事前に池谷　真 (mikeya@cira.kyoto-u.ac.jp) に連絡をとり、分与に関して許可を得ること。(2) 当該マウスを用いる論文発表に際しては Accession No. CDB0402K、その WEB サイト（https://large.riken.jp/distribution/mutant-list.html）とともに当該マウスを記載すること。(3) 当該マウスを用いる論文発表に際しては、その由来として第一報論文（Development, 133, 4463-4473 (2006).）を引用すること。(4)発表論文を寄託者 (mutant.bdr@riken.jp)に連絡すること。
DepositorRIKEN CDB（独立行政法人理化学研究所）
Strain Status凍結胚のアイコン凍結胚
Strain Availability受注後、検査を施して提供
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

BRC mice in Publications

No Data