Strain Information | |
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Image | |
BRC No. | RBRC04547 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6.129S-Ticam1<tm2Tsse> |
Former Common name | TICAM-1 (Trif) KO |
H-2 Haplotype | |
ES Cell line | CCE/EK.CCE [129S/SvEv-Gpi1<c>] |
Background strain | |
Appearance | |
Strain development | Developed by Tsukasa Seya, Graduate School of Medicine, Hokkaido University in 2007. |
Strain description | |
Colony maintenance | |
References | TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction. Oshiumi H, Matsumoto M, Funami K, Akazawa T, Seya T Nat. Immunol., 4, 161-167 (2003). 12539043 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |||||||
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Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
Ticam1 | TIR domain containing adaptor molecule 1 | 17 | Ticam1 | targeted mutation 2, Tsukasa Seya | |||
neo | neomycin resistance gene (E. coli) | 17 | herpes simplex virus thymidine kinase promoter (HSV tk promoter) |
Phenotype | |
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Annotation by Mammalian phenotyhpe ontology | |
Detailed phenotype data |
Ordering Information | |
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Donor DNA | herpes simplex virus thymidine kinase promoter (HSV tk promoter), E. coli Neomycin resistance gene, mouse Ticam1 genomic DNA |
Research application | Immunology and Inflammation Research Virology Research |
Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Nat. Immunol., 4, 161-167 (2003). |
Depositor | Tsukasa Seya (Hokkaido University) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |