Strain Data Sheet

RBRC04495

Strain Information

Image
BRC No.RBRC04495
TypeTransgeneCartagena
SpeciesMus musculus
Strain nameB6.Cg-Tg(Tek-cre)1Ywa
Former Common nameTie2-Cre, B6-TekCre Tg
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentThe University of Texas Southwestern Medical Center・柳沢正史先生。混合背景。
Strain descriptionTek-cre (Tie2-cre) トランスジェニックマウス。マウスTekプロモーター制御下で、cre recombinase遺伝子を発現するトランスジェニックマウス。
Colony maintenanceCarrier x Noncarrier [or Crossing to C57BL/6N(Crlj)]
ReferencesJ. Clin. Invest., 108, 537-546 (2001). 11518727
Dev. Biol., 230, 230-242 (2001). 11161575

Health Report

Examination Date / Room / Rack2024/01/09Room:3-ARack:G
2023/10/16Room:3-ARack:G
2023/10/10Room:3-ARack:G
2023/07/10Room:3-ARack:G
2023/04/10Room:3-ARack:G
2023/02/13Room:3-ARack:G
2023/01/10Room:3-ARack:G
2022/10/11Room:3-ARack:G
2022/07/11Room:3-ARack:G

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Mt1mouse metallothionein-1(MT-1) polyA signalUNMt1

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
crePhage P1 Cre recombinaseUNcretransgene insertion 1, Masashi Yanagisawamouse endothelial-specific receptor tyrosine kinase promoter

Ordering Information

供与核酸mouse Tie2 promoter, Phage P1 Cre, mouse metallothionein-1(MT-1) poly A signal, mouse Tie2 intron 1 enhancer
Research applicationCre/loxP system
提供条件条件を付加する。
研究成果の公表にあたって寄託者の指定する文献を引用する。Dev. Biol., 230, 230-242 (2001).
Depositor limits the use of the BIOLOGICAL RESOURCE to not-for-profit institutions. Depositor limits the use of the BIOLOGICAL RESOURCE to academic purposes. For-profit institutions and recipients who intend to use BIOLOGICAL RESOURCE for commercial research purposes shall acquire prior written consent from the Depositor. Recipient shall acquire prior written consent from the Depositor prior to filing an application for patent, or intellectual property or other rights based on the results of research using the BIOLOGICAL RESOURCE.
Depositor柳沢　正史（University of Texas Southwestern Medical Center at Dallas）
Strain Status生体のアイコン生体
凍結胚のアイコン凍結胚
凍結精子のアイコン凍結精子
Strain Availability凍結精子を1ヶ月以内に提供可能
凍結胚を1ヶ月以内に提供可能
生体マウスを1~3ヶ月以内に提供可能
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)
Lab HP
Genotyping protocol -PCR-

BRC mice in Publications

Arai HN, Sato F, Yamamoto T, Woltjen K, Kiyonari H, Yoshimoto Y, Shukunami C, Akiyama H, Kist R, Sehara-Fujisawa A.
Metalloprotease-Dependent Attenuation of BMP Signaling Restricts Cardiac Neural Crest Cell Fate.
Cell Rep 29(3) 603-616.e5(2019) 31618630

Sawaguchi S, Varshney S, Ogawa M, Sakaidani Y, Yagi H, Takeshita K, Murohara T, Kato K, Sundaram S, Stanley P, Okajima T.
O-GlcNAc on NOTCH1 EGF repeats regulates ligand-induced Notch signaling and vascular development in mammals.
Elife 6 (2017) 28395734

Kakae M, Nakajima H, Tobori S, Kawashita A, Miyanohara J, Morishima M, Nagayasu K, Nakagawa T, Shigetomi E, Koizumi S, Mori Y, Kaneko S, Shirakawa H.
The astrocytic TRPA1 channel mediates an intrinsic protective response to vascular cognitive impairment via LIF production.
Sci Adv 9(29) eadh0102(2023) 37478173