Strain Data Sheet

RBRC04488

Strain Information

Image
BRC No.RBRC04488
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameC.129P2(B6)-Sirpa<tm1Nog>
Former Common nameSIRP alpha ミュータントマウス
H-2 Haplotype
ES Cell lineE14.1 [129P2/OlaHsd]
Background strainBALB/cAJcl
Appearance
Strain development開発者 / 機関 : 神戸大学129Sv系統由来ES細胞(E14.1)にターゲッティングベクターを導入し作製。C57BL/6Nと5世代戻し交配後、Balb/cと15世代戻し交配、その後兄妹交配で維持。
Strain description膜タンパク質SIRPalpha の機能解析に使用
Colony maintenance兄妹交配
ReferencesJ. Biol. Chem., 277 (42) 39833-9 (2002). 12167615
EMBO J., 19, 6721-6731 (2000). 11118207

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Sirpasignal-regulatory protein alpha2Sirpa<tm1Nog>targeted mutation 1, Tetsuya NoguchiBit, CD172a, P84, SHPS-1, SIRP; Ptpns1;protein tyrosine phosphatase, non-receptor type substrate 1

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
neoneomycin resistance gene (E. coli)2neo; neomycin;mouse phosphoglycerate kinase promoter (PGK promoter)

Ordering Information

供与核酸mouse phosphoglycerate kinase promoter (PGK promoter), E. coli neo, PGK PolyA, mouse Sirpa genomic DNA
Research applicationImmunology and Inflammation Research
提供条件条件を付加する。
寄託者の承諾を得る。
Depositor的崎　尚（国立大学法人群馬大学）
Strain Status凍結精子のアイコン凍結精子
Strain Availability凍結精子より作出したマウスを2~4ヶ月以内に提供可能
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)
Lab HP
Genotyping protocol -PCR-

BRC mice in Publications

No Data