Strain Information | |
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Image | |
BRC No. | RBRC04434 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6.129-Msi1<tm1Okn> |
Former Common name | |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | Developed by Shinsuke Shibata and Hideyuki Okano, Keio University School of Medicine. |
Strain description | Msi1 deficient miceC57BL/6J background Msi1 deficient mice frequently died of obstructive hydrocephalus within a couple of month with aberrant cell proliferation around cerebral aqueduct. (Sakakibara S et al. Proc Natl Acad Sci USA. 2002) Both male and female are infertile because of the early death of hydrocephalus.On the other hand, CD-1 (ICR) background Msi1 deficient mice survive to adult without gross anatomical phenotype. Since both male and female are fertile, it is possible to mate between Msi1 null mice. (Unpublished data) |
Colony maintenance | |
References | Proc. Natl. Acad. Sci. USA, 99, 15194-15199 (2002). 12407178 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)5neo; neomycin;mouse phosphoglycerate kinase promoter (PGK promoter) |
Ordering Information | |
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供与核酸 | mouse Musashi1 genomic DNA, E. coli Tn5neo gene, mouse PGK promoter, SV40 polyA |
Research application | Cell Biology Research |
提供条件 | 条件を付加する。 研究成果の公表にあたって寄託者の指定する文献を引用する。Proc. Natl. Acad. Sci. USA, 99, 15194-15199 (2002). 利用希望者は、事前に利用条件等につき寄託者と合意し、提供承諾を得ること。 |
Depositor | 岡野 栄之(慶應義塾大学) |
Strain Status | 凍結精子 |
Strain Availability | 凍結精子より作出したマウスを2~4ヶ月以内に提供可能 凍結精子を1ヶ月以内に提供可能 |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |