Strain Data Sheet

RBRC04357

Strain Information

Image
BRC No.RBRC04357
TypeTransgeneCartagena
SpeciesMus musculus
Strain nameC57BL/6J-Tg(hSMA-NCX1.3)1
Former Common nameHSMA-N1.3-Tg
H-2 Haplotype
ES Cell line
Background strainC57BL/6
Appearance
Strain developmentDeveloped by Takahiro Iwamoto, School of Medicine, Fukuoka University in 2003.
Strain description
Colony maintenance
References
Salt-sensitive hypertension is triggered by Ca2+ entry via Na+/Ca2+ exchanger type-1 in vascular smooth muscle.
Iwamoto T, Kita S, Zhang J, Blaustein M P, Arai Y, Yoshida S, Wakimoto K, Komuro I, Katsuragi T
Nat Med., 10, 1193-1199 (2004). 15475962

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Slc8a1 solute carrier family 8 (sodium/calcium exchanger), member 1UNSlc8a1 NCX1.3human smooth muscle alpha-actin promoter
Slc8a1 solute carrier family 8 (sodium/calcium exchanger), member 1UNSlc8a1 NCX1.1human smooth muscle alpha-actin promoter

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • coronary artery stenosis(MP:0003024)
    • Detailed phenotype data

    Ordering Information

    Donor DNAhuman smooth muscle alpha-actin promoter, dog NCX1.3 cDNA, SV40 polyA signal
    Research applicationcovid19_progression
    Specific Term and ConditionsThe RECIPIENT of BIOLOGICAL RESOURCE must obtain a prior written consent on use of it from the DEPOSITOR/DEVELOPER.
    DepositorTakahiro Iwamoto (Fukuoka University)
    Strain Statusan icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Cryopreserved embryos (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    BRC mice in Publications

    No Data