Strain Information | |
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Image | |
BRC No. | RBRC04198 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6.129P2-Cxcr4<tm2Tng> |
Former Common name | CXCR4 flox |
H-2 Haplotype | |
ES Cell line | E14.1 [129P2/OlaHsd] |
Background strain | |
Appearance | |
Strain development | Developed by Takashi Nagasawa, Resrarch institute, Osaka Medical Center for Maternal and Child Health. |
Strain description | |
Colony maintenance | |
References | Immunity, 20, 707-718 (2004). 15189736 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP1loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP1loxP |
Ordering Information | |
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Donor DNA | Phage P1 loxP sites, Mouse Cxcr4 genomic DNA |
Research application | Cre/loxP system |
Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT is requested to make a Material Transfer Agreement with the DEPOSITOR. For use of the BIOLOGICAL RESOURCE by a for-profit institution, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and must obtain a prior written consent form the DEPOSITOR. |
Depositor | Takashi Nagasawa (Kyoto University) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- Mouse of the Month Dec 2014 |
BRC mice in Publications |
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Kurita K, Ishikawa K, Takeda K, Fujimoto M, Ono H, Kumagai J, Inoue H, Yokoh H, Yokote K. CXCL12-CXCR4 pathway activates brown adipocytes and induces insulin resistance in CXCR4-deficient mice under high-fat diet. Sci Rep 9(1) 6165(2019) 30992469 |