Strain Information | |
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Image | |
BRC No. | RBRC04188 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | C57BL/6-Ceacam1<tm1.1Fta> |
Former Common name | cB61ba, C57BL/6-Ceacam1<tm1> |
H-2 Haplotype | |
ES Cell line | MS12 [C57BL/6] |
Background strain | C57BL/6 |
Appearance | |
Strain development | Developed by Fumihiro Taguchi, National Institute of Infectious Diseases in 2001. |
Strain description | 1-70 aminoacids in the N-domain of Caecam1 was replaced from C57BL/6 type CAECAM1a (1a) (MHV sensitive) to SJL type CAECAM1b (1b) (MHV resistant). |
Colony maintenance | |
References | Role of mouse hepatitis virus (MHV) receptor murine CEACAM1 in the resistance of mice to MHV infection: studies of mice with chimeric mCEACAM1a and mCEACAM1b. Hirai A, Ohtsuka N, Ikeda T, Taniguchi R, Blau D, Nakagaki K, Miura H S, Ami Y, Yamada Y K, Itohara S, Holmes K V, Taguchi F J. Virol., 84 (13) 6654-66 (2010). 20410265 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |||||||
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Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
Ceacam1 | CEA cell adhesion molecule 1 | 7 | Ceacam1 | targeted mutation 1.1, Fumihiro Taguchi | |||
Ceacam1b | carcinoembryonic antigen-related cell adhesion molecule 1 | 7 | Ceacam1b | ||||
loxP | phage P1 loxP | 7 | loxP |
Phenotype | |
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Annotation by Mammalian phenotyhpe ontology | |
Detailed phenotype data |
Ordering Information | |
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Donor DNA | mouse Ceacam1b cDNA, Phage P1 loxP site, mouse Ceacam1 genomic DNA |
Research application | Cre/loxP system Virology Research |
Specific Term and Conditions | No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.) |
Depositor | Asuka Hirai (National Institute of Infectious Diseases) |
Strain Status | Frozen embryos |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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No Data |