Strain Data Sheet

RBRC04188

Strain Information

Image
BRC No.RBRC04188
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameC57BL/6-Ceacam1<tm1.1Fta>
Former Common namecB61ba, C57BL/6-Ceacam1<tm1>
H-2 Haplotype
ES Cell lineMS12 [C57BL/6]
Background strainC57BL/6
Appearance
Strain developmentDeveloped by Fumihiro Taguchi, National Institute of Infectious Diseases in 2001.
Strain description1-70 aminoacids in the N-domain of Caecam1 was replaced from C57BL/6 type CAECAM1a (1a) (MHV sensitive) to SJL type CAECAM1b (1b) (MHV resistant).
Colony maintenance
References
Role of mouse hepatitis virus (MHV) receptor murine CEACAM1 in the resistance of mice to MHV infection: studies of mice with chimeric mCEACAM1a and mCEACAM1b.
Hirai A, Ohtsuka N, Ikeda T, Taniguchi R, Blau D, Nakagaki K, Miura H S, Ami Y, Yamada Y K, Itohara S, Holmes K V, Taguchi F
J. Virol., 84 (13) 6654-66 (2010). 20410265

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Ceacam1CEA cell adhesion molecule 17Ceacam1targeted mutation 1.1, Fumihiro Taguchi
Ceacam1bcarcinoembryonic antigen-related cell adhesion molecule 17Ceacam1b
loxPphage P1 loxP7loxP

Phenotype

Annotation by Mammalian phenotyhpe ontology
Detailed phenotype data

Ordering Information

Donor DNAmouse Ceacam1b cDNA, Phage P1 loxP site, mouse Ceacam1 genomic DNA
Research applicationCre/loxP system
Virology Research
Specific Term and ConditionsNo specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
DepositorAsuka Hirai (National Institute of Infectious Diseases)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved embryos (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

BRC mice in Publications

No Data