Strain Data Sheet

RBRC04102

Strain Information

Image
BRC No.RBRC04102
TypeInbred
SpeciesMus musculus
Strain nameCS/NgaEbiAbeh
Former Common nameCS
H-2 Haplotype
ES Cell line
Background strainCS
Appearance
Strain development
Strain description
Colony maintenance
References
Feeding cycles entrain circadian rhythms of locomotor activity in CS mice but not in C57BL/6J mice.
Abe H, Kida M, Tsuji K, Mano T
Physiol. Behav., 45, 397-401 (1989). 2756028

Functional diversities of two activity components of circadian rhythm in genetical splitting mice (CS strain).
Abe H, Honma S, Honma K, Suzuki T, Ebihara S
J. of Comparative Physiology., 184, 243-251 (1999). 10319444

Clock gene expressions in the suprachiasmatic nucleus and other areas of the brain during rhythm splitting in CS mice.
Abe H, Honma S, Namihira M, Masubuchi S, Ikeda M, Ebihara S, Honma K
Mol. Brain Res., 87, 92-99 (2001). 11223163

Behavioural rhythm splitting in the CS mouse is related to clock gene expression outside the suprachiasmatic nucleus.
Abe H, Honma S, Namihira M, Masubuchi S, Honma K
Eur. J. Neurosci., 14, 1121-1128 (2001). 11683904

Sleep properties of CS mice with spontaneous rhythm splitting in constant darkness.
Ebihara S, Miyazaki S, Sakamaki H, Yoshimura T
Brain Res., 980, 121-127 (2003). 12865166

Peripheral clock gene expression in CS mice with bimodal locomotor rhythms.
Watanabe T, Kojima M, Tomida S, Nakamura T J, Yamamura T, Nakao N, Yasuo S, Yoshimura T, Ebihara S
Neurosci. Res., 54, 295-301 (2006). 16442179

Daily restricted feeding resets the circadian clock in the suprachiasmatic nucleus of CS mice.
Abe H, Honma S, Honma K
Am. J. Physiol. Regul. Integr. Comp. Physiol., 292, R607-R615 (2007). 16990494

Usp46 is a quantitative trait gene regulating mouse immobile behavior in the tail suspension and forced swimming tests.
Tomida S, Mamiya T, Sakamaki H, Miura M, Aosaki T, Masuda M, Niwa M, Kameyama T, Kobayashi J, Iwaki Y, Imai S, Ishikawa A, Abe K, Yoshimura T, Nabeshima T, Ebihara S
Nat. Genet., 41, 688-695 (2009). 19465912

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Usp46
MGI:1916977
ubiquitin specific peptidase 465Usp46
MGI:5438646
CS

Phenotype

Phenotype annotation from literatures by Mammalian phenotype ontology
  • abnormal anxiety-related response (MP:0001362)

  • abnormal depression-related behavior (MP:0003360)

  • abnormal nest building behavior (MP:0001447)

  • improved righting response (MP:0002863)
  • Detailed phenotype data

    Ordering Information

    Donor DNA
    Research application
    Specific Term and ConditionsIn publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The RECIPIENT of BIOLOGICAL resource shall obtain a prior written consent on use of it from the DEPOSITOR (Prof. Hiroshi Abe, University of Fukui Faculty of Medical Sciences or Prof, Shizufumi Ebihara, Graduate School of Bioagricultural Sciences, Nagoya University). The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
    DepositorDrs. Shizufumi Ebihara and Hiroshi Abe (Nagoya University/ University of Fukui)
    Strain Statusan icon for Frozen embryosFrozen embryos
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved embryos (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

    BRC mice in Publications

    No Data