Strain Data Sheet
RBRC04067
Strain Information | |
|---|---|
| Image | |
| BRC No. | RBRC04067 |
| Type | Transgene |
| Species | Mus musculus |
| Strain name | B6.B6D2-Tg(CAG-Ddr2) |
| Former Common name | |
| H-2 Haplotype | |
| ES Cell line | |
| Background strain | |
| Appearance | |
| Strain development | |
| Strain description | |
| Colony maintenance | |
| References | A novel dwarfism with gonadal dysfunction due to loss-of-function allele of the collagen receptor gene, Ddr2, in the mouse. Kano K, Marin de Evsikova C, Young J, Wnek C, Maddatu T P, Nishina P M, Naggert J K Mol. Endocrinol., 22, 1866-1880 (2008). 18483174Transcriptome analysis reveals an unexpected role of a collagen tyrosine kinase receptor gene, Ddr2, as a regulator of ovarian function. Matsumura H, Kano K, Marin de Evsikova C, Young J A, Nishina P M, Naggert J K, Naito K Physiol. Genomics., 39, 120-129 (2009). 19671659Discoidin domain receptor 2 (DDR2) is required for maintenance of spermatogenesis in male mice. Kano K, Kitamura A, Matsuwaki T, Morimatsu M, Naito K Mol. Reprod. Dev., 77, 29-37 (2010). 19681157 |
Health Report | |
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| Examination Date / Room / Rack | |
Gene | |||||||
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| Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
| Ddr2 | discoidin domain receptor family, member 2 | UN | Ddr2 | CAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA) | |||
Phenotype | |
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| Phenotype annotation from literatures by Mammalian phenotype ontology | |
| Detailed phenotype data | |
Ordering Information | |
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| Donor DNA | mouse Discoidin Domain Receptor 2, chicken beta-actin promoter, rabbit beta-globin poly A, CMV IE enhancer |
| Research application | |
| Specific Term and Conditions | In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The RECIPIENT of BIOLOGICAL RESOURCE must obtain a prior written consent on use of it from the DEPOSITOR/DEVELOPER. |
| Depositor | Kiyoshi Kano (The University of Tokyo) |
| Strain Status |  Frozen sperm |
| Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
| Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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| No Data |