Strain Data Sheet

RBRC03823

Strain Information

Image
BRC No.RBRC03823
TypeTargeted Mutation and TransgeneCartagena
SpeciesMus musculus
Strain nameB6;129S1(Cg)-Oaz3<tm1Htan> Tg(CAG/Acr-EGFP)C3-N01-FJ002Osb
Former Common nameOAT-t disruption mouse, GFP-TG
H-2 Haplotype
ES Cell lineW9.5 [129S1/Sv-Oca2<+> Tyr<+> Kitl<+>]
Background strain
Appearance
Strain developmentDeveloped by Hiromitsu Tanaka, Nagasaki International University in 2009.
Strain description
Colony maintenance
References
OAZ-t/OAZ3 is essential for rigid connection of sperm tails to heads in mouse.
Tokuhiro K, Isotani A, Yokota S, Yano Y, Oshio S, Hirose M, Wada M, Fujita K, Ogawa Y, Okabe M, Nishimune Y, Tanaka H
PLoS Genet., 5, 1-7, (2009). 19893612

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Oaz3
MGI:1858170		ornithine decarboxylase antizyme 33Oaz3<tm1Htan>
MGI:4462794		targeted mutation 1, Hiromitsu Tanaka
GFP Green Fluorescent Protein (Aequorea victoria)UN mouse proacrosin promoter, mouse proacrosin signal peptide, acrosin N-terminal peptide
GFP Green Fluorescent Protein (Aequorea victoria)UN CAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA)

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • detached sperm flagellum(MP:0008893)

  • impaired acrosome reaction(MP:0004542)

  • male infertility(MP:0001925)
    • Detailed phenotype data

    Ordering Information

    Donor DNAE. coli neo, mouse mouse phosphoglycerate kinase promoter (PGK promoter), Jellyfish GFP cDNA, CAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA), mouse proacrosin promoter, mouse proacrosin signal peptide, acrosin N-terminal peptide, bovine growth hormone polyadenylation signal
    Research application
    Specific Term and ConditionsThe RECIPIENT of BIOLOGICAL RESOURCE must obtain a prior written consent on use of it from the DEPOSITOR/DEVELOPER. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
    DepositorHiromitsu Tanaka (Nagasaki International University)
    Strain Statusan icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. CAGGS MTA (English)
    4. Acceptance of responsibility for living modified organism (Japanese / English)

    BRC mice in Publications

    No Data