Strain Information | |
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Image | |
BRC No. | RBRC03708 |
Type | Spontaneous Mutation |
Species | Mus musculus |
Strain name | FLS.B6-Lep<ob>/Shi |
Former Common name | FLS-ob |
H-2 Haplotype | |
ES Cell line | |
Background strain | FLS |
Appearance | |
Strain development | Developed by Aburahi Laboratories, Shionogi Research Laboratories, Shionogi & Co., Ltd. in 1990. |
Strain description | |
Colony maintenance | |
References | Genetic typing of the mouse ob mutation by PCR and restriction enzyme analysis. Hirasawa T, Ohara T, Makino S Exp. Anim., 46, 75-78 (1997). 9027475Characterization of the effects of pancreatic polypeptide in the regulation of energy balance. Asakawa A, Inui A, Yuzuriha H, Ueno N, Katsuura G, Fujimiya M, Fujino M A, Niijima A, Meguid M M, Kasuga M Gastroenterology., 124, 1325-1336 (2003). 12730873Mol. Med., 36, 448-451 (1999). |
Health Report | |
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Examination Date / Room / Rack | 2024/08/26Room:4-BRack:J 2024/05/27Room:4-BRack:J 2024/02/26Room:4-BRack:J 2023/11/27Room:4-BRack:J 2023/08/28Room:4-BRack:J 2023/05/29Room:4-BRack:J 2023/02/27Room:4-BRack:J |
Gene | |||||||
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Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
Lep | leptin | 6 | Lep | obese |
Phenotype | |
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Annotation by Mammalian phenotyhpe ontology | more 174 phenotypes |
Detailed phenotype data |
Ordering Information | |
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Donor DNA | |
Research application | Cancer Research Metabolism Research Mouse Models for Human Disease |
Specific Term and Conditions | In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The RECIPIENT must inform the DEPOSITOR (srp-contact@shionogi.co.jp) the research plan using the BIOLOGICAL RESOURCE and must obtain a prior written consent from the DEPOSITOR using the APPROVAL FROM specified by the DEPOSITOR. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, the RECIPIENT must inform the DEPOSITOR of the contents of such publication in advance. The RECIPIENT must contact and discuss with the DEPOSITOR in case of filing a patent application based on research results by using the BIOLOGICAL RESOURCES. The RECIPIENT must contact and discuss with the DEPOSITOR in case of application for any commercial use. |
Depositor | Shionogi & Co., Ltd. (Shionogi & Co., Ltd) |
Strain Status | Live mice Frozen embryos Frozen sperm |
Strain Availability | Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) Live mouse (1 to 3 months) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |