Strain Data Sheet

RBRC03514

Strain Information

Image
BRC No.RBRC03514
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.Cg-Hgs<tm>/Rbrc
Former Common nameHrs(loxP)(Acc.No. CDB0476K)
H-2 Haplotype
ES Cell lineTT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1]
Background strain
Appearance
Strain developmentDeveloped by Kazuo Sugamura, Tohoku University Graduate School of Medicine in 2008. Deposited by Laboratory for Animal Resrouces and Genetic Engineering, RIKEN Center for Developmental Biology.
Strain descriptionHrs (Hgs, HGF-regulated tryosine kinase substrate) floxed mice. Conditional Hrs deficient mice can be generated by crossing with tissue-specific Cre mice.
Colony maintenance
ReferencesAm. J. Pathol., 173, 1806-1817 (2008). 19008375

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
HgsHGF-regulated tryosine kinase substrate11Hgs<tm>targeted mutation

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Frtyeast FRT (flippase recombination target) site11Frt

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Frtyeast FRT (flippase recombination target) site11Frt

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
loxPphage P1 loxP11loxP

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
loxPphage P1 loxP11loxP

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
neoneomycin resistance gene (E. coli)11mouse phosphoglycerate kinase promoter (PGK promoter)

Ordering Information

供与核酸mouse phosphoglycerate kinase promoter (PGK promoter), E.coli neo, Phage P1 loxP sites, yeast FRT (flipase recombination target) sites, mouse Hgs genomic DNA
Research applicationCre/loxP system
FLP/frt system
提供条件条件を付加する。
(1) 分与希望者は事前に 田中 伸幸 (tanaka@med.tohoku.ac.jp) に連絡をとり、分与に関して許可を得ること。(2) 当該マウスを用いる論文発表に際してはAccession No. CDB0476K、そのWEB サイトhttps://large.riken.jp/distribution/mutant-list.htmlとともに当該マウスを記載すること。(3) 当該マウスを用いる論文発表に際しては、その由来として第一報論文 Am J Pathol. 2008 173(6):1806-17. を引用すること。（4）発表論文を寄託者（mutant.bdr@riken.jp）に連絡すること。
DepositorRIKEN CDB（独立行政法人理化学研究所）
Strain Status凍結胚のアイコン凍結胚
凍結精子のアイコン凍結精子
Strain Availability凍結胚より作出したマウスを2~4ヶ月以内に提供可能
凍結精子を1ヶ月以内に提供可能
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

No Data