Strain Data Sheet

RBRC03330

Strain Information

Image
BRC No.RBRC03330
Type
SpeciesMus musculus
Strain nameFB1 KO
Former Common name
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain development
Strain description
Colony maintenance
References
SCRAPPER-dependent ubiquitination of active zone protein RIM1 regulates synaptic vesicle release.
Ikuko Yao, Hiroshi Takagi, Hiroshi Ageta, Tomoaki Kahyo, Showbu Sato, Ken Hatanaka, Yoshiyuki Fukuda, Tomoki Chiba, Nobuhiro Morone, Shigeki Yuasa, Kaoru Inokuchi, Toshihisa Ohtsuka, Grant R Macgregor, Keiji Tanaka, Mitsutoshi Setou
Cell, 130(5): 943-957 (2007). 17803915

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NamePromoterDiseases Related to This Gene
Fbxl20
F-box and leucine-rich repeat protein 2011
Fbxl20<tm1Seto>
targeted mutation 1, Mitsutoshi Setou
neo
neomycin resistance gene (E. coli)11

Phenotype

Phenotype annotation from literatures by Mammalian phenotype ontology
  • abnormal miniature excitatory postsynaptic currents(MP:0004753)

  • decreased body size(MP:0001265)

  • decreased paired-pulse facilitation(MP:0002920)

  • lethality throughout fetal growth and development, incomplete penetrance(MP:0011109)

  • premature death(MP:0002083)
    • more 1 phenotypes
  • small pancreas(MP:0004247)
    • Detailed phenotype data

    Ordering Information

    Donor DNAScrapper (FBXL20) genomic DNA (mouse), neo (E. coli)
    Research application
    Specific Term and ConditionsThe BIOLOGICAL RESOURCE shall be used only for academic research purposes by a non-profit organization.
    The RECIPIENT of a non-profit organization must prior contact RIKEN BRC and negotiate with Mitsubishi Chemical Corporation to use the BIOLOGICAL RESOURCE for purposes of other than academic research.
    In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE in relevant journals and meetings, the RECIPIENT must stipulate the source of the BIOLOGICAL RESOURCE and an acknowledgment to Mitsubishi Chemical Corporation.
    The RECIPIENT agrees that RIKEN BRC informs annually to Mitsubishi Chemical Corporation of RECIPIENT organization, RECIPIENT name, the specific research purpose and the date of distribution.
    DepositorMitsutoshi Setou (Mitsubishi Kasei Institute of Life Sciences)
    Strain Statusan icon for Frozen embryosFrozen embryos
    Strain AvailabilityRecovery and QC required prior to distribution
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    BRC mice in Publications

    No Data