Strain Data Sheet

RBRC03298

Strain Information

Image
BRC No.RBRC03298
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameALDP/ApoE KO
Former Common name
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain development
Strain description
Colony maintenance
References

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Apoe
MGI:88057		apolipoprotein E7Apoe targeted mutation
  • age related macular degeneration 1(MedGEN)

  • Alzheimer disease 2(DisGeNET, MedGEN)

  • Alzheimer disease 3(MedGEN)
    • more 4 Diseases
  • Alzheimer disease 4(MedGEN)

  • hyperlipoproteinemia type 3(DisGeNET, MedGEN)

  • lipoprotein glomerulopathy(DisGeNET, MedGEN)

  • sea-blue histiocyte syndrome(MedGEN)
    • neo neomycin resistance gene (E. coli)7
    Abcd1
    MGI:1349215    		ATP-binding cassette, sub-family D member 1XAbcd1
    MGI:2429945    		targeted mutation 1, Takeshi Yamada
  • adrenoleukodystrophy(MedGEN)
    • neo neomycin resistance gene (E. coli)X

    Phenotype

    Annotation by Mammalian phenotyhpe ontology
  • abnormal lipid homeostasis(MP:0002118)
    • Detailed phenotype data

    Ordering Information

    Donor DNAmouse ALDP(ABCD1) genomic DNA, mouse Apoe genomic DNA, E. coli neo
    Research applicationCardiovascular Research
    Hematological Research
    Specific Term and ConditionsThe BIOLOGICAL RESOURCE shall be used only for academic research purposes by a non-profit organization.
    The RECIPIENT of a non-profit organization must prior contact RIKEN BRC and negotiate with Mitsubishi Chemical Corporation to use the BIOLOGICAL RESOURCE for purposes of other than academic research.
    In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE in relevant journals and meetings, the RECIPIENT must stipulate the source of the BIOLOGICAL RESOURCE and an acknowledgment to Mitsubishi Chemical Corporation.
    The RECIPIENT agrees that RIKEN BRC informs annually to Mitsubishi Chemical Corporation of RECIPIENT organization, RECIPIENT name, the specific research purpose and the date of distribution.
    DepositorNaohiro Hashimoto (Mitsubishi Kasei Institute of Life Sciences)
    Strain Statusan icon for Frozen embryosFrozen embryos
    Strain AvailabilityRecovery and QC required prior to distribution
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    BRC mice in Publications

    No Data