Strain Data Sheet



BRC No.RBRC03241
TypeTargeted Mutation and TransgeneCartagena
SpeciesMus musculus
Strain nameB6.Cg-Tg(TCRaTCRb) Rag2<tm1>/Rbrc
Former Common nameBOG8 Tg
H-2 Haplotype
ES Cell line
Background strain
Strain development
Strain description
Colony maintenance
ReferencesEur. J. Immunol., 26(9): 2081-2086 (1996). 8814250
Int. Immunol. 1996 8(3): 297-306. 8671615

Health Report

Examination Date / Room / Racknull


Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Rag2recombination activating gene 22Rag2

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
TcraT cell receptor alpha chainUNTcra

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
TcrbT cell receptor beta chainUNTcrb


Donor DNAMMLVプロモーターを上流に持つマウスTCRAVJ48C1遺伝子のcDNAとマウスTCRBV8.2DJ1.1C2を含むマウスTCRbeta鎖のgenomic DNAを挿入した。RAG-2遺伝子のexonをNeo遺伝子に置換
Research application
Specific Term and ConditionsThe BIOLOGICAL RESOURCE shall be used only for academic research purposes by a non-profit organization.
The RECIPIENT of a non-profit organization must prior contact RIKEN BRC and negotiate with Mitsubishi Chemical Corporation to use the BIOLOGICAL RESOURCE for purposes of other than academic research.
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE in relevant journals and meetings, the RECIPIENT must stipulate the source of the BIOLOGICAL RESOURCE and an acknowledgment to Mitsubishi Chemical Corporation.
The RECIPIENT agrees that RIKEN BRC informs annually to Mitsubishi Chemical Corporation of RECIPIENT organization, RECIPIENT name, the specific research purpose and the date of distribution.
DepositorMakoto Iwata (Mitsubishi Kasei Institute of Life Sciences)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)
Dr Iwata Lab (English)

BRC mice in Publications

No Data