Strain Information | |
|---|---|
| Image | |
| BRC No. | RBRC03074 |
| Type | Transgene |
| Species | Mus musculus |
| Strain name | C57BL/6J-Tg(hSMA-NCX1.3*G833C)1 |
| Former Common name | HSMA-N1.3G833C-Tg |
| H-2 Haplotype | |
| ES Cell line | |
| Background strain | C57BL/6JJmsSlc |
| Appearance | |
| Strain development | 開発者/機関:岩本隆宏先生/福岡大学医学部薬理学開発年:2003年 |
| Strain description | NCX1.3は血管平滑筋細胞のCa2+濃度調節に関わる重要なCa2+輸送体である。本輸送体の血管平滑筋特異的高発現マウスは軽度な高血圧を呈する。NCX1.3のG833C変異体は阻害薬に非感受性となる。血管トーヌス制御、高血圧等の研究に有用である。 |
| Colony maintenance | 兄妹交配 |
| References | |
Health Report | |
|---|---|
| Examination Date / Room / Rack | |
Gene | |||||||
|---|---|---|---|---|---|---|---|
| Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
| Slc8a1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | UN | Slc8a1 | human Smooth muscle alpha-actin promoter | |||
Phenotype | |
|---|---|
| Phenotype annotation from literatures by Mammalian phenotype ontology | |
| Detailed phenotype data | |
Ordering Information | |
|---|---|
| 供与核酸 | human smooth muscle α-actin promoter, Dog NCX1.3 G833C mutant cDNA, SV40 polyA signal |
| Research application | Cell Biology Research Hematological Research covid19_progression |
| 提供条件 | 寄託者(開発者)の承諾を得る。 |
| Depositor | 岩本 隆宏(福岡大学) |
| Strain Status | 凍結胚 凍結精子 |
| Strain Availability | 凍結胚より作出したマウスを2~4ヶ月以内に提供可能 凍結精子を1ヶ月以内に提供可能 凍結胚を1ヶ月以内に提供可能 |
| Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
|---|
| No Data |