Strain Information | |
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Image | |
BRC No. | RBRC02849 |
Type | Targeted Mutation Congenic |
Species | Mus musculus |
Strain name | B6.Cg-Ern1<tm1Dron> |
Former Common name | Irel alpa knockout mouse +/- strain:129/C57BL/Black Swiss Webster |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | black [a/a B/B C/C] |
Strain development | Mixed (129, B6 and Swiss Webster)Gene targeting was achieved in W4 ES cells |
Strain description | Homozygous Ire1alpha- null mice are embryonic lethal |
Colony maintenance | Diet for breeding is preferable but not essential. |
References | Science, 287, 664-666 (2000). 10650002 Nature, 415, 92-96 (2002). 11780124 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Ern1endoplasmic reticulum (ER) to nucleus signaling 111Ern1<tm1Dron>targeted mutation 1, David Rontargeted mutation 1, David Ron Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)11neo; neomycin;mouse phosphoglycerate kinase promoter (PGK promoter) |
Ordering Information | |
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供与核酸 | mouse Ern1 genomic DNA, mouse phosphoglycerate kinase promoter (PGK promoter), E. coli Neomycin phosphotransferase |
Research application | |
提供条件 | 条件を付加する。利用者は事前に寄託者の提供承諾書を得る。 研究成果の公表にあたって寄託者の指定する文献を引用する。Science, 287, 664-666 (2000). Nature, 415, 92-96 (2002). 研究成果の公表にあたって謝辞の表明を必要とする。 DEPOSITOR hereby excludes any and all warranties, implied or express, including warranties of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE or of non-infringement of patents or other proprietary right. The sample of BIOLOGOCAL RESOURCE is provided "as is". In no event shall DEPOSITOR be liable for direct, indirect, special, incidental or consequential damages in connection with the BIOLOGICAL RESOURCE. RECIPIENT and RIKEN BRC will indemnify and hold DEPOSITOR harmless from any claims or liability resulting from the use of the BIOLOGICAL RESOURCE by you. Prior to filing an application for a patent, or intellectual property or other rights based on the results of research using the BIOLOGICAL RESOURCE, the recipient shall acquire the consent form the DEPOSITOR for such application. |
Depositor | David Ron(New York University School of Medicine) |
Strain Status | 凍結胚 凍結精子 |
Strain Availability | 凍結胚より作出したマウスを2~4ヶ月以内に提供可能 凍結精子を1ヶ月以内に提供可能 凍結胚を1ヶ月以内に提供可能 |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |