Strain Data Sheet
RBRC02847
Strain Information | |
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| Image | |
| BRC No. | RBRC02847 |
| Type | Targeted Mutation |
| Species | Mus musculus |
| Strain name | 129S6/SvEvTac-Dkk3<tm1Tfur> |
| Former Common name | DKK3 K.O. |
| H-2 Haplotype | |
| ES Cell line | TC1 [129S6/SvEvTac] |
| Background strain | 129S6/SvEvTac |
| Appearance | light-bellied agouti [A<w>/A<w> B/B C/C] |
| Strain development | 2007. Takahisa Furuawa10世代 129SvEv |
| Strain description | 調べた限りphenotypeなし |
| Colony maintenance | 特に注意点なし |
| References | |
Health Report | |
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| Examination Date / Room / Rack | |
Gene | |
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| Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Dkk3dickkopf homolog 3 (Xenopus laevis)7Dkk3<tm1Tfur>targeted mutation 1, Takahisa Furukawadickkopf homolog 3 (Xenopus laevis) Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)7neo; neomycin;mouse phosphoglycerate kinase promoter (PGK promoter) Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter SV40 polyA signal7 |
Ordering Information | |
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| 供与核酸 | mouse phosphoglycerate kinase promoter (PGK promoter), E. coli neo, SV40 pA, mouse Dkk3 genomic DNA |
| Research application | |
| 提供条件 | 条件を付加する。 研究成果の公表にあたって謝辞の表明を必要とする。 |
| Depositor | 古川 貴久（大阪バイオサイエンス研究所） |
| Strain Status |  凍結胚 凍結精子 |
| Strain Availability | 凍結胚より作出したマウスを2~4ヶ月以内に提供可能 凍結胚を1ヶ月以内に提供可能 |
| Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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Habuta M, Fujita H, Sato K, Bando T, Inoue J, Kondo Y, Miyaishi S, Kumon H, Ohuchi H. Dickkopf3 (Dkk3) is required for maintaining the integrity of secretory vesicles in the mouse adrenal medulla. Cell Tissue Res 379(1) 157-167(2020) 31673758 Zhu Y, Demidov ON, Goh AM, Virshup DM, Lane DP, Bulavin DV. Phosphatase WIP1 regulates adult neurogenesis and WNT signaling during aging. J Clin Invest 124(7) 3263-73(2014) 24911145 Inoue J, Fujita H, Bando T, Kondo Y, Kumon H, Ohuchi H. Expression analysis of Dickkopf-related protein 3 (Dkk3) suggests its pleiotropic roles for a secretory glycoprotein in adult mouse. J Mol Histol 48(1) 29-39(2017) 27866302 |