Strain Data Sheet

RBRC02846

Strain Information

Image
BRC No.RBRC02846
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain name129S6/SvEvTac-Crx<tm1Clc>
Former Common nameCRX K.O.
H-2 Haplotype
ES Cell line
Background strain129S6/SvEvTac
Appearancelight-bellied agouti [A<w>/A<w> B/B C/C]
Strain development1999. Takahisa Furukawa, Harvard Medical School60世代 129SvEv (Taconic) (100%)
Strain description網膜視細胞外節の欠損盲目
Colony maintenance特に注意点なし形態の異常・奇形がある
ReferencesNat. Genet., 23, 466-470 (1999). 10581037

Health Report

Examination Date / Room / Rack2022/07/11Room:3-BRack:K
2022/06/13Room:3-BRack:K

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Crxcone-rod homeobox containig gene7Crx<tm1Clc>targeted mutation 1, Constance L Cepkocone-rod homeobox containg gene

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
neoneomycin resistance gene (E. coli)7neo; neomycin;mouse phosphoglycerate kinase promoter (PGK promoter)

Ordering Information

供与核酸mouse phosphoglycerate kinase promoter (PGK promoter), E. coli neo, SV40 polyA, mouse Crx genomic DNA
Research application
提供条件条件を付加する。
研究成果の公表にあたって寄託者の指定する文献を引用する。Nat. Genet., 23, 466-470 (1999).
Depositor古川　貴久（大阪バイオサイエンス研究所）
Strain Status凍結胚のアイコン凍結胚
凍結精子のアイコン凍結精子
Strain Availability凍結胚より作出したマウスを2~4ヶ月以内に提供可能
凍結胚を1ヶ月以内に提供可能
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

Iura Y, Udo H.
Behavioral analyses of visually impaired Crx knockout mice revealed sensory compensation in exploratory activities on elevated platforms.
Behav Brain Res 258 1-7(2014) 24140563