Strain Data Sheet

Williams PA, Naughton KE, Simon LA, Soto GE, Parham LR, Ma X, Danan CH, Hu W, Friedman ES, McMillan EA, Mehta H, Stoltz MA, Soto Ocaña J, Zackular J, Bittinger K, Whelan KA, Karakasheva TA, Hamilton KE.
Intestinal epithelial autophagy is required for the regenerative benefit of calorie restriction.
Am J Physiol Gastrointest Liver Physiol (2023) 36852920

Luo P, Yan H, Du J, Chen X, Shao J, Zhang Y, Xu Z, Jin Y, Lin N, Yang B, He Q.
PLK1 (polo like kinase 1)-dependent autophagy facilitates gefitinib-induced hepatotoxicity by degrading COX6A1 (cytochrome c oxidase subunit 6A1).
Autophagy 17(10) 3221-3237(2021) 33315519

Muralimanoharan S, Gao X, Weintraub S, Myatt L, Maloyan A.
Sexual dimorphism in activation of placental autophagy in obese women with evidence for fetal programming from a placenta-specific mouse model.
Autophagy 12(5) 752-69(2016) 26986453

Wang Y, Liu X, Zhu L, Li W, Li Z, Lu X, Liu J, Hua W, Zhou Y, Gu Y, Zhu M.
PG545 alleviates diabetic retinopathy by promoting retinal Müller cell autophagy to inhibit the inflammatory response.
Biochem Biophys Res Commun 531(4) 452-458(2020) 32800548

Mizushima N, Yoshimori T, Levine B.
Methods in mammalian autophagy research.
Cell 140(3) 313-26(2010) 20144757

Song ZH, Yu HY, Wang P, Mao GK, Liu WX, Li MN, Wang HN, Shang YL, Liu C, Xu ZL, Sun QY, Li W.
Germ cell-specific Atg7 knockout results in primary ovarian insufficiency in female mice.
Cell Death Dis 6(1) e1589(2015) 25590799

Yan B, Belke D, Gui Y, Chen YX, Jiang ZS, Zheng XL.
Pharmacological inhibition of MALT1 (mucosa-associated lymphoid tissue lymphoma translocation protein 1) induces ferroptosis in vascular smooth muscle cells.
Cell Death Discov 9(1) 456(2023) 38097554

Walter KM, Schönenberger MJ, Trötzmüller M, Horn M, Elsässer HP, Moser AB, Lucas MS, Schwarz T, Gerber PA, Faust PL, Moch H, Köfeler HC, Krek W, Kovacs WJ.
Hif-2α promotes degradation of mammalian peroxisomes by selective autophagy.
Cell Metab 20(5) 882-897(2014) 25440060

Klochkova A, Karami AL, Fuller AD, Parham LR, Panchani SR, Natarajan S, Jackson JL, Mu A, Tan Y, Cai KQ, Klein-Szanto AJ, Muir AB, Tétreault MP, Graña X, Hamilton KE, Whelan KA.
Autophagy Contributes to Homeostasis in Esophageal Epithelium Where High Autophagic Vesicle Level Marks Basal Cells With Limited Proliferation and Enhanced Self-Renewal Potential.
Cell Mol Gastroenterol Hepatol 18(1) 15-40(2024) 38452871

Parham LR, Williams PA, Katada K, Nettleford SK, Chatterji P, Acheampong KK, Danan CH, Ma X, Simon LA, Naughton KE, Karakasheva T, McMillan EA, Whelan KA, Brady DC, Shaffer SM, Hamilton KE.
IGF2BP1/IMP1 deletion enhances a facultative stem cell state via regulation of MAP1LC3B.
Cell Mol Gastroenterol Hepatol (2023) 38081361

Wang H, Wan H, Li X, Liu W, Chen Q, Wang Y, Yang L, Tang H, Zhang X, Duan E, Zhao X, Gao F, Li W.
Atg7 is required for acrosome biogenesis during spermatogenesis in mice.
Cell Res 24(7) 852-69(2014) 24853953

Bang S, Lee GK, Shin H, Suh CS, Lim HJ.
Vitrification, in vitro fertilization, and development of Atg7 deficient mouse oocytes.
Clin Exp Reprod Med 43(1) 9-14(2016) 27104152

Chatterji P, Williams PA, Whelan KA, Samper FC, Andres SF, Simon LA, Parham LR, Mizuno R, Lundsmith ET, Lee DS, Liang S, Wijeratne HS, Marti S, Chau L, Giroux V, Wilkins BJ, Wu GD, Shah P, Tartaglia GG, Hamilton KE.
Posttranscriptional regulation of colonic epithelial repair by RNA binding protein IMP1/IGF2BP1.
EMBO Rep 20(6) (2019) 31061170

Kang X, Yang W, Feng D, Jin X, Ma Z, Qian Z, Xie T, Li H, Liu J, Wang R, Li F, Li D, Sun H, Wu S.
Cartilage-Specific Autophagy Deficiency Promotes ER Stress and Impairs Chondrogenesis in PERK-ATF4-CHOP-Dependent Manner.
J Bone Miner Res 32(10) 2128-2141(2017) 28304100

Li KC, Wang CH, Zou JJ, Qu C, Wang XL, Tian XS, Liu HW, Cui T.
Loss of Atg7 in Endothelial Cells Enhanced Cutaneous Wound Healing in a Mouse Model.
J Surg Res 249 145-155(2020) 31958599

Zhang Y, Cross SD, Stanton JB, Marmorstein AD, Le YZ, Marmorstein LY.
Early AMD-like defects in the RPE and retinal degeneration in aged mice with RPE-specific deletion of Atg5 or Atg7.
Mol Vis 23 228-241(2017) 28465655

Song Y, Na H, Lee SE, Kim YM, Moon J, Nam TW, Ji Y, Jin Y, Park JH, Cho SC, Lee J, Hwang D, Ha SJ, Park HW, Kim JB, Lee HW.
Dysfunctional adipocytes promote tumor progression through YAP/TAZ-dependent cancer-associated adipocyte transformation.
Nat Commun 15(1) 4052(2024) 38744820

Tan HWS, Lu G, Dong H, Cho YL, Natalia A, Wang L, Chan C, Kappei D, Taneja R, Ling SC, Shao H, Tsai SY, Ding WX, Shen HM.
A degradative to secretory autophagy switch mediates mitochondria clearance in the absence of the mATG8-conjugation machinery.
Nat Commun 13(1) 3720(2022) 35764633

Luciani A, Schumann A, Berquez M, Chen Z, Nieri D, Failli M, Debaix H, Festa BP, Tokonami N, Raimondi A, Cremonesi A, Carrella D, Forny P, Kölker S, Diomedi Camassei F, Diaz F, Moraes CT, Di Bernardo D, Baumgartner MR, Devuyst O.
Impaired mitophagy links mitochondrial disease to epithelial stress in methylmalonyl-CoA mutase deficiency.
Nat Commun 11(1) 970(2020) 32080200