Strain Data Sheet

RBRC02692

Strain Information

Image
BRC No.RBRC02692
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.129X1-Lilrb4a<tm1Ttk>
Former Common namegp49B
H-2 Haplotype
ES Cell lineRW4 [129X1/SvJ]
Background strainC57BL/6NCrlCrlj
Appearanceblack [a/a B/B C/C]
Strain development開発者／機関：東北大学加齢医学研究所　遺伝子導入分野
Strain description免疫発現遺伝子であるgp49B遺伝子を欠損させたマウスを解析し，免疫発現遺伝子である免疫反応に与える影響を検討する。
Colony maintenance・兄妹交配特記：ホモ×ホモ・戻し交配Background系統名：C57BL/6N (チャールズリバー)
ReferencesEur. J. Immunol., 38 (9) 2426-37 (2008). 18792399
J. Immunol., 165, 4970-4977 (2000). 11046024
J. Biol. Chem., 273, 1070-1074 (1998). 9422771

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Lilrb4aleukocyte immunoglobulin-like receport, subfamily B, member 410Lilrb4a<tm1Ttk>targeted mutation 1, Toshiyuki TakaiCD85K, Gp49b, HM18, ILT3, Lilrb4

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
neoneomycin resistance gene (E. coli)10neo; neomycin;mouse phosphoglycerate kinase promoter (PGK promoter)

Ordering Information

供与核酸mouse phosphoglycerate kinase promoter (PGK promoter), E. coli neo, mouse Lilrb4a genomic DNA
Research applicationImmunology and Inflammation Research
提供条件条件を付加する。
研究成果の公表にあたって寄託者の指定する文献を引用する。J. Biol. Chem., 273, 1070-1074 (1998). J. Immunol., 165, 4970-4977 (2000).
Depositor高井　俊行（国立大学法人東北大学）
Strain Status凍結胚のアイコン凍結胚
凍結精子のアイコン凍結精子
Strain Availability凍結胚より作出したマウスを2~4ヶ月以内に提供可能
凍結精子を1ヶ月以内に提供可能
凍結胚を1ヶ月以内に提供可能
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

Li Z, Zhao M, Li T, Zheng J, Liu X, Jiang Y, Zhang H, Hu X.
Decidual Macrophage Functional Polarization during Abnormal Pregnancy due to Toxoplasma gondii: Role for LILRB4.
Front Immunol 8 1013(2017) 28883820