Strain Data Sheet



BRC No.RBRC02481
TypeTargeted Mutation and TransgeneCartagena
SpeciesMus musculus
Strain nameB6.Cg-Hras1<tm1Mok> Tg(HRAS)2Mok Tg(Hras)1Mok
Former Common nameH-ras-KO, rasH2 Tg, mouse H-ras Tg, B6-Hras KO/HRAS Tg#2/Hras Tg
H-2 Haplotype
ES Cell line
Background strain
Strain developmentDeveloped by Motoya Katsuki, National Institutes of Natural Sciences.
Strain descriptionHras knockout, human HRAS transgene and mouse Hras transgene triple mutant mice.
Colony maintenance
ReferencesOncogene, 5, 1195-1200 (1990). 2202951
Oncogene, 19, 2951-2956 (2000). 10871846

Health Report

Examination Date / Room / Racknull


Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
HrasHarvey rat sarcoma virus oncogene7Hras<tm1Mok>targeted mutation 1, Motoya Katsukic-H-ras, c-rasHa, H-ras, Ha-ras, Harvey-ras, Hras-1, ras

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
neoneomycin resistance gene (E. coli)7


Donor DNAE. coli neo, mouse H-ras, human H-ras
Research application
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Oncogene, 19, 2951-2956 (2000). Oncogene, 5, 1195-1200 (1990).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to Dr. Motoya Katsuki is requested. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
DepositorToshikuni Sasaoka (Niigata University)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

BRC mice in Publications

No Data