Strain Data Sheet



BRC No.RBRC02476
TypeTargeted Mutation CongenicCartagena
SpeciesMus musculus
Strain nameB6.Cg-Kras<tm1Mok> Il6st<tm1>
Former Common nameB6-Kras/gp130 KO
H-2 Haplotype
ES Cell line
Background strain
Strain developmentDeveloped by Motoya Katsuki, National Institutes of Natural Sciences.
Strain descriptionKras and gp130 (Il6st) genes double knockout mice.
Colony maintenance
ReferencesOncogene, 15, 1151-1159 (1997). 9294608

Health Report

Examination Date / Room / Racknull


Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Il6stinterleukin 6 signal transducer13Il6st<tm1>targeted mutation 1

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Krasv-Ki-ras2 Kirsten rat sarcome viral oncogene homolog6Kras<tm1Mok>targeted mutation 1, Motoya Katsuki


Donor DNAE. coli neo, mouse K-ras genomic DNA, mouse gp130 genomic DNA
Research applicationcovid19_onset
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Oncogene, 15, 1151-1159 (1997).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to Dr. Motoya Katsuki is requested. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
DepositorToshikuni Sasaoka (Niigata University)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

BRC mice in Publications

No Data