Strain Data Sheet

RBRC02475

Information1

Image
BRC No.RBRC02475
TypeTargeted Mutation CongenicCartagena
SpeciesMus musculus
Strain nameB6.Cg-Hras1<tm1Mok> Nras<tm1Mok> Il6st<tm1>
Former Common nameB6-Hras/Nras/gp130 KO
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeveloped by Motoya Katsuki, National Institutes of Natural Sciences.
Strain descriptionHras, Nras and gp130 (Il6st) genes triple knockout mice.
Colony maintenance
ReferencesEMBO J. 21(5):1021-30 (2002). 11867530
Oncogene, 19(26):2951-2956 (2000). 10871846

Health Report

Examination Date / Room / Racknull

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Il6stinterleukin 6 signal transducer13Il6st<tm1>targeted mutation 1

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Csde1cold shock domain containing E1, RNA binding3Csde1

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Nrasneuroblastoma ras oncogene3Nras<tm1Mok>targeted mutation 1, Motoya Katsuki

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
neoneomycin resistance gene (E. coli)3neo; neomycin;herpes simplex virus thymidine kinase promoter (HSV tk promoter)

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
HrasHarvey rat sarcoma virus oncogene7Hras<tm1Mok>targeted mutation 1, Motoya Katsukic-H-ras, c-rasHa, H-ras, Ha-ras, Harvey-ras, Hras-1, ras

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
neoneomycin resistance gene (E. coli)7

Information2

Donor DNAE. coli neo, mouse H-ras genomic DNA, mouse N-ras genomic DNA, mouse gp130 genomic DNA
Research applicationcovid19_onset
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Oncogene, 19, 2951-2956 (2000). EMBO J., 21, 1021-1030 (2002).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to Dr. Motoya Katsuki is requested. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
DepositorToshikuni Sasaoka (Niigata University)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

BRC mice in Publications

No Data