Strain Data Sheet

RBRC02392

Strain Information

Image
BRC No.RBRC02392
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.129P2-Jdp2<tm2Kkyo>/Rbrc
Former Common nameB6.129P2-Jundm2<tm2>
H-2 Haplotype
ES Cell lineE14 [129P2/OlaHsd]
Background strainC57BL/6
Appearanceblack [a/a B/B C/C]
Strain developmentDeveloped by Drs. Yokoyama KK and Pan J, RIKEN BioResource Center. The E14 ES cells originated from 129P2/OlaHsd were used. The knock-out mice are under backcrossing to C57BL/6J strain.
Strain descriptionJDP2 coding region was disrupted.
Colony maintenanceHeterozygote x Wild-type [C57BL/6J]
References

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Jdp2Jun dimerization protein 212Jdp2<tm2Kkyo>targeted mutation 2, Kazunari K YokoyamaJdp2, TIF

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Frtyeast FRT (flippase recombination target) site12Frt

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Frtyeast FRT (flippase recombination target) site12Frt

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
loxPphage P1 loxP12loxP

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
loxPphage P1 loxP12loxP

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
neoneomycin resistance gene (E. coli)12mouse phosphoglycerate kinase promoter (PGK promoter)

Ordering Information

供与核酸phage P1 loxP sites, mouse phosphoglycerate kinase promoter (PGK promoter), E. coli neo, S. cerevisiae Frt sites, mouse JDP2 genomic DNA
Research applicationCre/loxP system
FLP/frt system
提供条件条件を付加する。
利用者は事前に開発者の横山和尚（kazu@kmu.edu.tw）に連絡をとり、使用許可を得る。
Depositor小幡　裕一（独立行政法人理化学研究所）
Strain Status凍結胚のアイコン凍結胚
凍結精子のアイコン凍結精子
Strain Availability凍結胚より作出したマウスを2~4ヶ月以内に提供可能
凍結精子を1ヶ月以内に提供可能
凍結胚を1ヶ月以内に提供可能
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

Yao C, Yao GQ, Sun BH, Zhang C, Tommasini SM, Insogna K.
The transcription factor T-box 3 regulates colony-stimulating factor 1-dependent Jun dimerization protein 2 expression and plays an important role in osteoclastogenesis.
J Biol Chem 289(10) 6775-6790(2014) 24394418