Strain Information | |
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Image | |
BRC No. | RBRC02193 |
Type | Transgene Congenic |
Species | Mus musculus |
Strain name | B6.Cg-Tg(hCD2-CA-AhR/GFP)A |
Former Common name | T-cell-specific CA-AhR Tg, Line A |
H-2 Haplotype | |
ES Cell line | |
Background strain | C57BL/6JJcl |
Appearance | |
Strain development | |
Strain description | |
Colony maintenance | |
References | Constitutively active aryl hydrocarbon receptor expressed specifically in T-lineage cells causes thymus involution and suppresses the immunization-induced increase in splenocytes. Nohara K, Pan X, Tsukumo S, Hida A, Ito T, Nagai H, Inouye K, Motohashi H, Yamamoto M, Fujii-Kuriyama Y, Tohyama C J. Immunol. 174, 2770-2777 (2005). 15728486Constitutive activation of the aryl hydrocarbon receptor in T-lineage cells induces thymus involution independently of the Fas/Fas ligand signaling pathway. Nagai H, Kubo M, Abe R, Yamamoto M, Nohara K Int. Immunopharmacol. 6, 279-286 (2006). 16399633 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |||||||
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Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
CA-AhR | constitutively active aryl-hydrocarbon receptor (AhR) | UN | CA-AhR | human CD2 promoter | |||
GFP | Green Fluorescent Protein (Aequorea victoria) | UN | human CD2 promoter |
Phenotype | |
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Annotation by Mammalian phenotyhpe ontology | |
Detailed phenotype data |
Ordering Information | |
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Donor DNA | mouse Arylhydrocarbon receptor (PAS B deletion mutant), Green Fluorescent Protein, human CD2 Promoter (5kb promeoter, 5.5 kb LCR), human K14 polyA |
Research application | Apoptosis Research Cell Biology Research Fluorescent Proteins/lacZ System Immunology and Inflammation Research |
Specific Term and Conditions | The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. The RECIPIENT agrees to include the DEPOSITOR as a co-author in any publications resulted by the use of the BIOLOGICAL RESOURCE. The RECIPIENT should contact the DEPOSITOR in the case of application for any patents or commercial use with the results from the use of the BIOLOGICAL RESOURCE. |
Depositor | Keiko Nohara (National Institute for Environmental Studies) |
Strain Status | Frozen embryos |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
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BRC mice in Publications |
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No Data |