Strain Data Sheet

RBRC02189

Strain Information

Image
BRC No.RBRC02189
TypeTransgeneCartagena
SpeciesMus musculus
Strain nameC57BL/6Cr-Tg(Pcdh21-cre)BYoko
Former Common namePcdh21-nCre, C57BL/6
H-2 Haplotype
ES Cell line
Background strainC57BL/6NCrSlc
Appearanceblack [a/a B/B C/C]
Strain development開発者：横井峰人先生機関名：京都大学開発年：2004年
Strain description嗅球mitral/tufted cellに選択的にCreリコンビナーゼを発現するトランスジェニックマウス。
Colony maintenance戻し交配系統名（ブリーダー名）：C57BL/6CrSlc、日本SLC
ReferencesGenesis, 43, 12-16 (2005). 16106355

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
crePhage P1 Cre recombinaseUNcrePcdh21 promoter

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
tTAtTA (E. coli tet repressor (TetR), herpes simplex virus (HSV) VP16 activation domain)UNtTAE. coli tet repressor (TetR), herpes simplex virus (HSV)VP16 activation domainPcdh21 promoter

Ordering Information

供与核酸FLAG tag, tTA (E. coli tet repressor (TetR), herpes simplex virus (HSV)VP16 activation domain), human FGF2-IRES, nuclear localization signal, Phage P1 Cre recombinase, rabbit beta-globin intron/polyA signal, mouse pcdh21 genomic DNA
Research applicationCre/loxP system
Neurobiology Research
Tet system
提供条件条件を付加する。
研究成果の公表にあたって寄託者の指定する文献を引用する。Genesis, 43, 12-16 (2005).
Depositor横井　峰人（国立大学法人京都大学）
Strain Status凍結胚のアイコン凍結胚
凍結精子のアイコン凍結精子
Strain Availability凍結胚より作出したマウスを2~4ヶ月以内に提供可能
凍結精子を1ヶ月以内に提供可能
凍結胚を1ヶ月以内に提供可能
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

Genotyping protocol -PCR-
Genetic Background

BRC mice in Publications

Fujimoto S, Leiwe MN, Aihara S, Sakaguchi R, Muroyama Y, Kobayakawa R, Kobayakawa K, Saito T, Imai T.
Activity-dependent local protection and lateral inhibition control synaptic competition in developing mitral cells in mice.
Dev Cell (2023) 37290446

Inoue N, Nishizumi H, Ooyama R, Mogi K, Nishimori K, Kikusui T, Sakano H.
The olfactory critical period is determined by activity-dependent Sema7A/PlxnC1 signaling within glomeruli.
Elife 10 (2021) 33780330

Miller JE, Granados-Fuentes D, Wang T, Marpegan L, Holy TE, Herzog ED.
Vasoactive intestinal polypeptide mediates circadian rhythms in mammalian olfactory bulb and olfaction.
J Neurosci 34(17) 6040-6(2014) 24760863

Iwata R, Kiyonari H, Imai T.
Mechanosensory-Based Phase Coding of Odor Identity in the Olfactory Bulb.
Neuron 96(5) 1139-1152.e7(2017) 29216451