Strain Data Sheet

RBRC02138

Strain Information

Image
BRC No.RBRC02138
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6;129P2(Cg)-Omp<tm4(cre)Mom>/MomTyagRbrc
Former Common nameOMP-Cre
H-2 Haplotype
ES Cell lineE14 [129P2/OlaHsd]
Background strain
Appearance
Strain developmentThe Rockefeller University・Peter Mombaerts（2001）。
Strain description成熟嗅神経に強く発現するOMP (olfactory marker protein) 遺伝子座にCreを挿入したノックインマウス。
Colony maintenanceHeterozygote x Wild-type [or Crossing to C57BL/6J(Crlj)]
References
Odorant receptor gene choice is reset by nuclear transfer from mouse olfactory sensory neurons.
Li J, Ishii T, Feinstein P, Mombaerts P
Nature 428, 393-399 (2004). 15042081

The protocadherin-alpha family is involved in axonal coalescence of olfactory sensory neurons into glomeruli of the olfactory bulb in mouse.
Hasegawa S, Hamada S, Kumode Y, Esumi S, Katori S, Fukuda E, Uchiyama Y, Hirabayashi T, Mombaerts P, Yagi T
Mol Cell Neurosci, 38, 66-79 (2008). 18353676

Health Report

Examination Date / Room / Rack2024/11/18Room:4-ARack:F
2024/08/19Room:4-ARack:F
2024/05/20Room:4-ARack:F
2024/02/19Room:4-ARack:F

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Frt yeast FRT (flippase recombination target) site7Frt
Frt yeast FRT (flippase recombination target) site7Frt
Omp
MGI:97436		olfactory marker protein7Omp<tm4(cre)Mom>
MGI:3692980		targeted mutation 4 (cre), Peter Mombaerts
cre Phage P1 Cre recombinase7cre Omp
neo neomycin resistance gene (E. coli)7 mouse phosphoglycerate kinase promoter (PGK promoter)

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • obsolete no phenotypic analysis(MP:0003012)
    • Detailed phenotype data

    Ordering Information

    供与核酸phage P1 Cre recombinase DNA, yeast FRT (flipase recombination target) sites, mouse phosphoglycerate kinase promoter (PGK promoter), E. coli neo, mouse Omp genomic DNA
    Research applicationFLP/frt system
    General Purpose
    Neurobiology Research
    提供条件利用者は提供承諾書を用いて、事前に寄託者の承諾を得る。利用者は事前にThe Rockefeller University・Peter Monbaerts教授の許可を得る。本リソースを用いた研究が発明に至った場合、利用者はその発明を開示するとともに、取り扱いについて寄託者と協議する。また、利用者は本リソースを用いた研究を公表する際は事前に寄託者に内容を開示し許可を得る事。利用者が非営利目的の教育・研究用に用いる場合以外は、大阪大学と別途MTAを締結すること。
    Depositor八木　健（国立大学法人大阪大学）
    Strain Status生体のアイコン生体
    凍結胚のアイコン凍結胚
    凍結精子のアイコン凍結精子
    Strain Availability凍結胚を1ヶ月以内に提供可能
    生体マウスを1~3ヶ月以内に提供可能
    Additional Info.Necessary documents for ordering:
    1. Approval form (Japanese / English)
    2. Order form (Japanese / English)
    3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    4. Acceptance of responsibility for living modified organism (Japanese / English)
    Lab HP (Japanese), Co-creation Bureau, Osaka University HP
    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data