Strain Data Sheet

RBRC01953

Strain Information

Image
BRC No.RBRC01953
TypeTargeted Mutation CongenicCartagena
SpeciesMus musculus
Strain nameB6.Cg-Pax1<tm1(LHED)Jtak>
Former Common namePax1tm1(LHED)Tak
H-2 Haplotype
ES Cell lineV6.5 [(C57BL/6J x 129S4/SvJae)F1]
Background strain
Appearance
Strain development
Strain description
Colony maintenance
References
A transposon-based chromosomal engineering method to survey a large cis-regulatory landscape in mice.
Kokubu C, Horie K, Abe K, Ikeda R, Mizuno S, Uno Y, Ogiwara S, Ohtsuka M, Isotani A, Okabe M, Imai K, Takeda J
Nat. Genet., 41:946-952 (2009). 19633672

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Frt yeast FRT (flippase recombination target) site2Frt
Pax1
MGI:97485		paired box 12Pax1<tm1(LHED)Jtak> targeted mutation 1 (LHED), Junji Takeda
  • otofaciocervical syndrome 2(MedGEN)
    • lacZ beta-galactosidase (E. coli)2
    loxP phage P1 loxP2loxP
    neo neomycin resistance gene (E. coli)2 mouse phosphoglycerate kinase promoter (PGK promoter)
    tetO tetracycline operator (E. coli)2tetO

    Phenotype

    Annotation by Mammalian phenotyhpe ontology
  • no abnormal phenotype detected(MP:0002169)
    • Detailed phenotype data

    Ordering Information

    Donor DNAMouse Phosphoglycerate kinase promoter, Mouse Hsp68 promoter, E. coli LacZ gene,E. coli Neomycin resistance gene, E. coli Tetracycline operator, Fish Sleeping Beauty transposon (IR/DR), P1 phage LoxP, Yeast FRT
    Research applicationCre/loxP system
    FLP/frt system
    Fluorescent Proteins/lacZ System
    Tet system
    Specific Term and ConditionsThe RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Nat. Genet., 41:946-952 (2009).RECIPIENT which wants to use the BIOLOGICAL RESOURCE for the purpose other than education or not-for-profit research is requested to enter into a Material Transfer Agreement with Osaka University.
    DepositorJunji Takeda (Osaka University)
    Strain Statusan icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Cryopreserved embryos (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Approval form (Japanese / English)
    2. Order form (Japanese / English)
    3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    4. Acceptance of responsibility for living modified organism (Japanese / English)
    Takeda Lab HP, Co-creation Bureau, Osaka University HP

    BRC mice in Publications

    No Data