Strain Data Sheet

RBRC01937

Strain Information

Image
BRC No.RBRC01937
TypeConsomic
SpeciesMus musculus
Strain nameC3H/HeN-11,14<NSY>
Former Common nameC3H.NSY-11,14 double consomic
H-2 Haplotype
ES Cell line
Background strainC3H/HeN
Appearance
Strain development
Strain description
Colony maintenanceSibling Mating (Homozygote x Homozygote)
References
Genetic analysis of late-onset type 2 diabetes in a mouse model of human complex trait.
Ueda H, Ikegami H, Kawaguchi Y, Fujisawa T, Yamato E, Shibata M, Ogihara T
Diabetes, 48, 1168-1174 (1999). 10331425

Susceptibility to streptozotocin-induced diabetes is mapped to mouse chromosome 11.
Babaya N, Ikegami H, Fujisawa T, Nojima K, Itoi-Babaya M, Inoue K, Ohno T, Shibata M, Ogihara T
Biochem. Biophys. Res. Commun., 328, 158-164 (2005). 15670764

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene

Phenotype

Phenotype annotation from literatures by Mammalian phenotype ontology
  • decreased insulin secretion (MP:0003059)

  • hyperglycemia (MP:0001559)

  • impaired glucose tolerance (MP:0005293)

  • increased body mass index (MP:0006087)

  • increased body weight (MP:0001260)
    • more 4 phenotypes
  • increased total fat pad weight (MP:0008908)

  • increased white adipose tissue amount (MP:0000008)

  • insulin resistance (MP:0005331)

  • obese (MP:0001261)
    • Detailed phenotype data

    Ordering Information

    Donor DNA
    Research applicationDiabetes and Obesity Research
    covid19_progression
    Specific Term and ConditionsThe RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. The RECIPIENT agrees to use this BIOLOGICAL RESOURCE as a collaboration with the DEPOSITOR.
    DepositorHiroshi Ikegami (Osaka University)
    Strain Statusan icon for Frozen embryosFrozen embryos
    Strain AvailabilityRecovery and QC required prior to distribution
    Additional Info.Necessary documents for ordering:
    1. Approval form (Japanese / English)
    2. Order form (Japanese / English)
    3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

    BRC mice in Publications

    No Data