Strain Data Sheet

RBRC01905

Strain Information

Image
BRC No.RBRC01905
TypeConsomic
SpeciesMus musculus
Strain nameC3H/HeN-14<NSY>
Former Common nameC3H-14NSY consomic
H-2 Haplotype
ES Cell line
Background strainC3H/HeN
Appearance
Strain development
Strain descriptionThis consomic strain was produced by backcrossing of the NSY Chr14 onto the C3H/HeN. This strain set is useful for the Quantitative Trait Loci mapping, a segregation analysis and a linkage mapping.
Colony maintenanceSibling Mating (Homozygote x Homozygote)
References
Genetic analysis of late-onset type 2 diabetes in a mouse model of human complex trait.
Ueda H, Ikegami H, Kawaguchi Y, Fujisawa T, Yamato E, Shibata M, Ogihara T
Diabetes, 48, 1168-1174 (1999). 10331425

Susceptibility to streptozotocin-induced diabetes is mapped to mouse chromosome 11.
Babaya N, Ikegami H, Fujisawa T, Nojima K, Itoi-Babaya M, Inoue K, Ohno T, Shibata M, Ogihara T
Biochem. Biophys. Res. Commun., 328, 158-164 (2005) 15670764

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • hyperglycemia(MP:0001559)

  • impaired glucose tolerance(MP:0005293)

  • increased body weight(MP:0001260)

  • increased circulating glucose level(MP:0005559)

  • increased circulating insulin level(MP:0002079)
  • more 3 phenotypes
  • increased epididymal fat pad weight(MP:0009288)

  • increased total fat pad weight(MP:0008908)

  • insulin resistance(MP:0005331)
  • Detailed phenotype data

    Ordering Information

    Donor DNA
    Research applicationDiabetes and Obesity Research
    covid19_progression
    Specific Term and ConditionsThe RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. The RECIPIENT agrees to use this BIOLOGICAL RESOURCE as a collaboration with the DEPOSITOR.
    DepositorHiroshi Ikegami (Osaka University)
    Strain Statusan icon for Frozen embryosFrozen embryos
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved embryos (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Approval form (Japanese / English)
    2. Order form (Japanese / English)
    3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

    BRC mice in Publications

    No Data