Strain Data Sheet

RBRC01773

Strain Information

Image
BRC No.RBRC01773
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6;129S2-Tmbim1<tm1Noj>/26
Former Common nameRECS1 KO
H-2 Haplotype
ES Cell lineD3 [129S2/SvPas]
Background strain
Appearance
Strain development大阪大学微生物病研究所・Hanjun Zhao、薮田紀一先生、野島　博先生（2001）。D3 ES細胞を用いて作出。
Strain descriptionRECS1 (Tmbim1) 遺伝子のノックアウトマウス。エクソン1から6をPGK-neoカセットで置換。ホモマウスは繁殖性、妊性あり。14ヶ月齢以上になると、血管中膜の嚢胞性の退行の傾向がある。
Colony maintenanceHeterozygote x Homozygote [or Crossing to C57BL/6NCrSlc]
ReferencesGenes Genet Syst., 81, 41-50 (2006). 16607040

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Tmbim1transmembrane BAX inhibitor motif containing 11Tmbim1<tm1Noj>targeted mutation 1, Hiroshi NojimaRECS1

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
neoneomycin resistance gene (E. coli)1neo; neomycin;mouse phosphoglycerate kinase promoter (PGK promoter)

Ordering Information

供与核酸mouse phosphoglycerate kinase promoter (PGK promoter), E. coli neo, mouse Tmbim1 genomic DNA
Research applicationMouse Models for Human Disease
提供条件条件を付加する。利用者は事前に寄託者の提供承諾書を得る。
研究成果の公表にあたって寄託者の指定する文献を引用する。RECS1 deficiency in mice induces susceptibility to cystic medical degeneration. Hanjun Zhao et al. (2006) Genes Genet. Syst. 81, p41-50
共同研究。
Depositor野島　博（国立大学法人大阪大学）
Strain Status凍結胚のアイコン凍結胚
Strain Availability受注後、検査を施して提供
Additional Info.Necessary documents for ordering:
  1. Approval form (Japanese / English)
  2. Order form (Japanese / English)
  3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  4. Acceptance of responsibility for living modified organism (Japanese / English)

Genotyping protocol -PCR-
Mouse of the Month Jan 2007

BRC mice in Publications

No Data