Strain Data Sheet

RBRC01770

Strain Information

Image
BRC No.RBRC01770
TypeWild-derived Inbred and Spontaneous Mutation
SpeciesMus musculus molossinus
Strain nameMSM;MA-Tyr<c>/RinRbrc
Former Common nameMSM/Ms-tyr<c>/Rin
H-2 Haplotype
ES Cell line
Background strainMSM [Mus musculus molossinus]
Appearance
Strain development開発者：前田幸子先生機関名：(財)東京都医学研究機構東京都臨床医学総合研究所MA/MyJ (♀) をMSM/Ms により backcross, inter-cross を8代経過したもの。
Strain description野生由来の近交系 MSM/Ms に MA/MyJ のtyrc locus を導入したものtyrc locus のhomozygous 個体はアルビノ状態を示す。
Colony maintenanceMSM/Ms にほぼ同じ。繁殖効率良好。
References

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Tyr
MGI:98880		tyrosinase7Tyr<c>
MGI:1855976		albino
  • oculocutaneous albinism type 1A(DisGeNET, MedGEN)

  • oculocutaneous albinism type 1B(MedGEN)

  • oculocutaneous albinism(DisGeNET)

    • Phenotype

    Phenotype annotation from literatures by Mammalian phenotype ontology
  • abnormal coat appearance (MP:0001510)

  • abnormal coat/hair pigmentation (MP:0002075)

  • abnormal eye pigmentation (MP:0001324)

  • absent coat pigmentation (MP:0005171)

  • absent eye pigmentation (MP:0008480)
    • more 5 phenotypes
  • belly spot (MP:0000373)

  • decreased eye pigmentation (MP:0005172)

  • diluted coat color (MP:0000371)

  • hypopigmentation (MP:0005408)

  • mottled coat (MP:0000421)
    • Detailed phenotype data

    Ordering Information

    供与核酸
    Research application
    提供条件条件を付加しない。
    Depositor米川　博通（(財)東京都医学研究機構東京都臨床医学総合研究所）
    Strain Status凍結胚のアイコン凍結胚
    Strain Availability凍結胚より作出したマウスを2~4ヶ月以内に提供可能
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    Mochida K, Hasegawa A, Otaka N, Hama D, Furuya T, Yamaguchi M, Ichikawa E, Ijuin M, Taguma K, Hashimoto M, Takashima R, Kadota M, Hiraiwa N, Mekada K, Yoshiki A, Ogura A.
    Devising assisted reproductive technologies for wild-derived strains of mice: 37 strains from five subspecies of Mus musculus.
    PLoS One 9(12) e114305(2014) 25470728