Strain Data Sheet

RBRC01745

Strain Information

Image
BRC No.RBRC01745
TypeConsomic
SpeciesMus musculus
Strain nameA/J-12<SM>
Former Common name
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeveloped by Tamio Ohno, Nagoya University Graduate School of Medicine.
Strain descriptionThese mice are a A/J-consomic strain carrying a chromosome from the SM/J strain introgressed into a A/J background. SM/J-derived Chr 2 (RBRC01743), SM/J-derived Chr 6 (RBRC01210), SM/J-derived Chr 11 (RBRC01742), SM/J-derived Chr 12 (RBRC01745), SM/J-derived Chr 13 (RBRC01209), SM/J-derived Chr 15 (RBRC01746), SM/J-derived Chr 17 (RBRC01747), SM/J-derived Chr 18 (RBRC01744), SM/J-derived Chr 19 (RBRC01748), SM/J-derived Chr Y (RBRC01598). This strain set is useful for the Quantitative Trait Loci mapping, a segregation analysis and a linkage mapping.
Colony maintenance
References
Searching for genetic factors of fatty liver in SMXA-5 mice by quantitative trait loci analysis under a high-fat diet.
Kumazawa M, Kobayashi M, Io F, Kawai T, Nishimura M, Ohno T, Horio F
J Lipid Res, 48(9): 2039-2046 (2007). 17595448

Establishment of consomic strains derived from A/J and SM/J mice for genetic analysis of complex traits.
Ohno T, Hata K, Baba T, Io F, Kobayashi M, Horio F, Nishimura M
Mamm Genome, 23(11-12):764-769 (2012). 23052825

Detection of differentially expressed candidate genes for a fatty liver QTL on mouse chromosome 12.
Kobayashi M, Suzuki M, Ohno T, Tsuzuki K, Taguchi C, Tateishi S, Kawada T, Kim Y I, Murai A, Horio F
BMC Genet, 17(1):73 (2016). 27266874

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • decreased circulating cholesterol level(MP:0005179)

  • decreased liver triglyceride level(MP:0009356)

  • decreased liver weight(MP:0003402)
    • Detailed phenotype data

    Ordering Information

    Donor DNA
    Research application
    Specific Term and ConditionsNo specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
    DepositorTamio Ohno (Nagoya University)
    Strain Statusan icon for Frozen embryosFrozen embryos
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

    BRC mice in Publications

    No Data