Strain Data Sheet

RBRC01742

Strain Information

Image
BRC No.RBRC01742
TypeConsomic
SpeciesMus musculus
Strain nameA/J-11<SM>
Former Common nameA.SM-Chr.11
H-2 Haplotype
ES Cell line
Background strainA
Appearance
Strain developmentDeveloped by Tamio Ohno, Nagoya University Graduate School of Medicine.
Strain descriptionThese mice are a A/J-consomic strain carrying a chromosome from the SM/J strain introgressed into a A/J background. SM/J-derived Chr 2 (RBRC01743), SM/J-derived Chr 6 (RBRC01210), SM/J-derived Chr 11 (RBRC01742), SM/J-derived Chr 12 (RBRC01745), SM/J-derived Chr 13 (RBRC01209), SM/J-derived Chr 15 (RBRC01746), SM/J-derived Chr 17 (RBRC01747), SM/J-derived Chr 18 (RBRC01744), SM/J-derived Chr 19 (RBRC01748), SM/J-derived Chr Y (RBRC01598). This strain set is useful for the Quantitative Trait Loci mapping, a segregation analysis and a linkage mapping.
Colony maintenance
References
Quantitative trait loci for impaired glucose tolerance in nondiabetic SM/J and A/J mice.
Natsuko Hada, Misato Kobayashi, Masato Fujiyoshi, Akira Ishikawa, Masako Kuga, Masahiko Nishimura, Shizufumi Ebihara, Tamio Ohno, Fumihiko Horio
Physiol Genomics, 35(1): 65-74 (2008). 18628340

Body and major organ weights of A/J-Chr 11(SM) consomic mice.
Shin Tanaka, Toshihiro Mizorogi, Kazutoshi Nishijima, Sachi Kuwahara, Masashi Tsujio, Hiroaki Aoyama, Chie Taguchi, Misato Kobayashi, Fumihiko Horio, Tamio Ohno
Exp Anim, 58(4): 357-361 (2009). 19654433

Establishment of consomic strains derived from A/J and SM/J mice for genetic analysis of complex traits.
Tamio Ohno, Keiko Hata, Taisuke Baba, Fusayo Io, Misato Kobayashi, Fumihiko Horio, Masahiko Nishimura
Mamm. Genome, 23(11-12):764-769 (2012). 23052825

Congenic mapping and candidate gene analysis for streptozotocin-induced diabetes susceptibility locus on mouse chromosome 11.
Tomoki Maegawa, Yuki Miyasaka, Misato Kobayashi, Naru Babaya, Hiroshi Ikegami, Fumihiko Horio, Masahide Takahashi, Tamio Ohno
Mamm. Genome, 29(3):273-280 (2018). 29523950

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene

Phenotype

Phenotype annotation from literatures by Mammalian phenotype ontology
  • decreased adrenal gland weight (MP:0013308)

  • decreased lung weight (MP:0005631)

  • decreased ovary weight (MP:0004856)

  • impaired glucose tolerance (MP:0005293)

  • increased body weight (MP:0001260)
    • more 3 phenotypes
  • increased brain weight (MP:0002176)

  • increased circulating triglyceride level (MP:0001552)

  • increased kidney weight (MP:0003917)
    • Detailed phenotype data

    Ordering Information

    Donor DNA
    Research application
    Specific Term and ConditionsNo specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
    DepositorTamio Ohno (Nagoya University)
    Strain Statusan icon for Frozen embryosFrozen embryos
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data